TcCLB.504075.10

kinetoplast poly(A) polymerase 1
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_139718 OG7: OG7_0019075 98 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 98 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.510533.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508169.9 ⚠
elongation factor 2, putative (fragment)
— OG7
TcCLB.511107.41 ⚠
ATP-dependent Clp protease subunit heat shock
— OG7
TcCLB.510963.90 ⚠
elongation factor 2, putative
— OG7
TcCLB.508169.20 ⚠
elongation factor 2, putative
— OG7
TcCLB.509125.20 ⚠
ATP-dependent Clp protease subunit, heat shoc
— OG7
TcCLB.509267.50 ⚠
U5 small nuclear ribonucleoprotein component,
— OG7
TcCLB.507875.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508807.10 ⚠
atp-dependent chaperone, ATP-dependent Clp pr
— OG7
TcCLB.511217.160 ⚠
WW domain containing protein, putative
— OG7
TcCLB.504077.40 ⚠
translation elongation factor EF-2, putative
— OG7
TcCLB.509965.350 ⚠
ubiquitin-protein ligase, putative
— OG7
TcCLB.511577.50 ⚠
endo-beta-N-acetylglucosaminidase, putative
— OG7
TcCLB.506413.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504427.140 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504097.10 ⚠
RNA editing complex protein MP61, putative
— OG7
TcCLB.416883.18 ⚠
proteasome alpha 2 subunit, putative
— OG7
TcCLB.510431.280 ⚠
RNA editing complex protein MP46, putative
— OG7
TcCLB.511145.43 ⚠
proteasome subunit alpha type-5, putative
— OG7
TcCLB.506167.40 ⚠
proteasome subunit alpha type-1, putative
— OG7
TcCLB.504213.120 ⚠
proteasome alpha 3 subunit, putative
— OG7
TcCLB.511867.50 ⚠
proteasome alpha 7 subunit, putative
— OG7
TcCLB.506885.350 ⚠
proteasome alpha 1 subunit, putative
— OG7
TcCLB.503613.20 ⚠
proteasome alpha 7 subunit, putative
— OG7
TcCLB.506211.40 ⚠
intraflagellar transport protein 52
— OG7
TcCLB.508277.360 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.503801.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510763.40 ⚠
proteasome complex subunit Rpn13 ubiquitin re
— OG7
TcCLB.510755.70 ⚠
proteasome complex subunit Rpn13 ubiquitin re
— OG7
TcCLB.508813.50 ⚠
oxidoreductase-like protein, putative
— OG7
TcCLB.506363.100 ⚠
mRNA processing protein, putative
— OG7
TcCLB.511621.180 ⚠
Phosducin, putative
— OG7
TcCLB.509069.20 ⚠
ATP binding protein-like protein, putative
— OG7
TcCLB.506221.50 ⚠
coatomer subunit epsilon
— OG7
TcCLB.509153.60 ⚠
lipin, putative
— OG7
TcCLB.508277.180 ⚠
mismatch repair protein MSH3, putative
— OG7
TcCLB.508183.4 ⚠
aspartyl aminopeptidase, putative (fragment)
— OG7
TcCLB.508647.210 ⚠
dynein arm light chain, putative
— OG7
TcCLB.508357.40 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TcCLB.510761.70 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.510749.40 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
TcCLB.506795.90 ⚠
'Cold-shock' DNA-binding domain containing pr
— OG7
TcCLB.506357.130 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509073.30 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.430737.20 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcCLB.509831.50 ⚠
intraflagellar transport protein 88, putative
— OG7
TcCLB.511911.102 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506205.20 ⚠
hypothetical protein
— OG7
TcCLB.506215.19 ⚠
intraflagellar transport protein 140, putativ
— OG7
TcCLB.506227.80 ⚠
mitochondrial DNA polymerase I protein B, put
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.