TcCLB.504427.140

hypothetical protein, conserved
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_136776 OG7: OG7_0043561 140 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:
Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 140 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.506357.130
hypothetical protein, conserved
— +2 more Both
TcCLB.504867.20
ABC transporter, putative
— Both
TcCLB.509073.30 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— Both
TcCLB.508357.40 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TcCLB.510749.40 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
TcCLB.510761.70 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.509165.49 ⚠
damage-specific DNA binding protein, putative
— Both
TcCLB.503893.150
Right handed beta helix region/Periplasmic co
— Both
TcCLB.503813.20 ⚠
hypothetical protein, conserved
— Both
TcCLB.505123.20 ⚠
hypothetical protein, conserved
— Both
TcCLB.506673.60 ⚠
Adaptor protein complex AP-3 subunit beta-3
— Both
TcCLB.506251.50
Cell division control protein 48, putative
— Both
TcCLB.511545.100 ⚠
RNA methyltransferase, putative
— Both
TcCLB.510773.9 ⚠
Thioredoxin-like/Protein of unknown function
— Both
TcCLB.504643.49
hypothetical protein, conserved (fragment)
— Both
TcCLB.503531.49 ⚠
structural maintenance of chromosome 3, putat
— Both
TcCLB.504883.60
hypothetical protein, conserved
— OG7
TcCLB.503777.19 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcCLB.506607.19 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcCLB.510431.250 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcCLB.508717.30 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcCLB.503897.20
hypothetical protein, conserved
— OG7
TcCLB.504159.80 ⚠
histone deacetylase, putative
— OG7
TcCLB.507641.14 ⚠
neurobeachin/beige protein, putative
— OG7
TcCLB.509011.20 ⚠
RNA polymerase IIA largest subunit, putative
— OG7
TcCLB.511113.9 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcCLB.508239.30 ⚠
neurobeachin/beige-like protein, putative
— OG7
TcCLB.507639.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511115.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504119.4 ⚠
DNA-directed RNA polymerase III subunit C1, p
— OG7
TcCLB.504051.20 ⚠
ATP-dependent DNA DEAD/DEAH box helicase, put
— OG7
TcCLB.509769.70 ⚠
DNA polymerase theta (helicase domain only),
— OG7
TcCLB.510243.50 ⚠
UMP/CMP kinase, putative
— OG7
TcCLB.504041.4 ⚠
RNA polymerase I
— OG7
TcCLB.507629.30 ⚠
Dpy-30 motif containing protein, putative
— OG7
TcCLB.506227.80 ⚠
mitochondrial DNA polymerase I protein B, put
— OG7
TcCLB.506657.70 ⚠
RNA editing 3' terminal uridylyl transferase
— OG7
TcCLB.504075.10 ⚠
kinetoplast poly(A) polymerase 1
— OG7
TcCLB.503903.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510753.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506223.120 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
TcCLB.506925.150 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.410961.10 ⚠
phosphatidylinositol kinase related protein,
— OG7
TcCLB.503989.60 ⚠
protein phosphatase 2C, putative (fragment)
— OG7
TcCLB.506739.200 ⚠
pyruvate dehydrogenase phosphatase
— OG7
TcCLB.510291.30 ⚠
protein phosphatase 2C-like, putative
— OG7
TcCLB.503637.20 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
TcCLB.510101.150 ⚠
adaptin-related protein-like, putative
— OG7
TcCLB.508779.90 ⚠
structural maintenance of chromosome protein
— OG7
TcCLB.507875.10 ⚠
hypothetical protein, conserved
— OG7
Page 1 of 3
Next →
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.