TcCLB.503893.150

Right handed beta helix region/Periplasmic copper-binding protein (NosD), putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_104692 OG7: OG7_0037636 146 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 146 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.506925.150 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.511801.4 ⚠
conserved hypothetical protein, conserved (fr
— Both
TcCLB.505123.20 ⚠
hypothetical protein, conserved
— Both
TcCLB.463673.9 ⚠
hypothetical protein, conserved
— Both
TcCLB.506673.60 ⚠
Adaptor protein complex AP-3 subunit beta-3
— Both
TcCLB.509067.40
NADH dehydrogenase subunit NI8M, putative
— Both
TcCLB.506251.50
Cell division control protein 48, putative
— Both
TcCLB.511545.100 ⚠
RNA methyltransferase, putative
— Both
TcCLB.510773.9 ⚠
Thioredoxin-like/Protein of unknown function
— Both
TcCLB.504643.49
hypothetical protein, conserved (fragment)
— Both
TcCLB.503971.10
2OG-Fe(II) oxygenase superfamily, putative
— Both
TcCLB.506743.210 ⚠
tubulin tyrosine ligase, putative
— Both
TcCLB.509951.49 ⚠
DNA-directed RNA polymerase II subunit 2, put
— OG7
TcCLB.511417.40 ⚠
DNA-directed RNA polymerase III, putative
— OG7
TcCLB.511313.30 ⚠
formin, putative
— OG7
TcCLB.511393.30 ⚠
formin homology 2 (FH2) domain protein, putat
— OG7
TcCLB.504883.60
hypothetical protein, conserved
— OG7
TcCLB.503777.19 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcCLB.506607.19 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcCLB.510431.250 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcCLB.508717.30 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcCLB.506221.30 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.420989.10 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.506659.39 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.509379.10 ⚠
dihydrolipoamide dehydrogenase, putative
— OG7
TcCLB.509151.80 ⚠
SpoU rRNA Methylase family, putative
— OG7
TcCLB.504137.60 ⚠
beta adaptin, putative
— OG7
TcCLB.511127.140 ⚠
DNA replication licensing factor MCM4, putati
— OG7
TcCLB.506533.34 ⚠
phosphatidylinositol kinase related protein,
— OG7
TcCLB.511435.49 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
TcCLB.503425.29 ⚠
DNA replication licensing factor MCM8, putati
— OG7
TcCLB.510293.40 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
TcCLB.511109.100 ⚠
DNA replication licensing factor MCM3, putati
— OG7
TcCLB.510409.39 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
TcCLB.509069.49 ⚠
DNA replication licensing factor MCM7, putati
— OG7
TcCLB.507757.70 ⚠
dihydrolipoamide dehydrogenase, putative, ace
— OG7
TcCLB.506223.120 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
TcCLB.508239.30 ⚠
neurobeachin/beige-like protein, putative
— OG7
TcCLB.507395.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511803.10 ⚠
cullin 2, putative
— OG7
TcCLB.511217.100 ⚠
cullin 3, putative
— OG7
TcCLB.503637.20 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
TcCLB.511075.40 ⚠
cullin, putative
— OG7
TcCLB.507641.14 ⚠
neurobeachin/beige protein, putative
— OG7
TcCLB.509011.20 ⚠
RNA polymerase IIA largest subunit, putative
— OG7
TcCLB.511113.9 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcCLB.508779.90 ⚠
structural maintenance of chromosome protein
— OG7
TcCLB.509769.70 ⚠
DNA polymerase theta (helicase domain only),
— OG7
TcCLB.510243.50 ⚠
UMP/CMP kinase, putative
— OG7
TcCLB.504051.20 ⚠
ATP-dependent DNA DEAD/DEAH box helicase, put
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.