TcCLB.506533.34

phosphatidylinositol kinase related protein, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_102827 OG7: OG7_0001934 322 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 322 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.508145.49 ⚠
hypothetical protein, conserved
— Both
TcCLB.507757.70 ⚠
dihydrolipoamide dehydrogenase, putative, ace
— OG7
TcCLB.507757.60 ⚠
dihydrolipoamide dehydrogenase, putative
— OG7
TcCLB.509379.10 ⚠
dihydrolipoamide dehydrogenase, putative
— OG7
TcCLB.509073.90 ⚠
CS domain/TPR repeat, putative
— OG7
TcCLB.503579.30 ⚠
DNA polymerase sigma-like protein, putative
— OG7
TcCLB.506179.59 ⚠
ATP-dependent RNA helicase, putative (fragmen
— OG7
TcCLB.509769.70 ⚠
DNA polymerase theta (helicase domain only),
— OG7
TcCLB.504051.20 ⚠
ATP-dependent DNA DEAD/DEAH box helicase, put
— OG7
TcCLB.511313.40 ⚠
ATP-dependent RNA helicase, putative
— OG7
TcCLB.511303.9 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506223.80 ⚠
Metalloprotease M41 FtsH, putative
— OG7
TcCLB.510105.210 ⚠
mitochondrial ATP-dependent zinc metallopepti
— OG7
TcCLB.511541.20 ⚠
hypothetical protein
— OG7
TcCLB.509893.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511047.50 ⚠
proteasome regulatory ATPase subunit 2, putat
— OG7
TcCLB.504147.200 ⚠
19S proteasome regulatory subunit, Regulatory
— OG7
TcCLB.508839.89 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
TcCLB.506859.20 ⚠
proteasome regulatory ATPase subunit 5, putat
— OG7
TcCLB.510311.70 ⚠
26S protease regulatory subunit, putative, se
— OG7
TcCLB.401473.9 ⚠
DNA-directed RNA polymerase I largest subunit
— OG7
TcCLB.504119.4 ⚠
DNA-directed RNA polymerase III subunit C1, p
— OG7
TcCLB.507739.20 ⚠
mitochondrial ATP-dependent zinc metallopepti
— OG7
TcCLB.511115.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.443683.9 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
TcCLB.507639.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.403789.9 ⚠
DNA-directed RNA polymerase I largest subunit
— OG7
TcCLB.508239.30 ⚠
neurobeachin/beige-like protein, putative
— OG7
TcCLB.507213.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511071.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511113.9 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcCLB.506949.10 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
TcCLB.509011.20 ⚠
RNA polymerase IIA largest subunit, putative
— OG7
TcCLB.507603.200 ⚠
proteasome regulatory ATPase subunit 3, putat
— OG7
TcCLB.507641.14 ⚠
neurobeachin/beige protein, putative
— OG7
TcCLB.507809.100 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511729.40 ⚠
60S ribosomal protein L9, putative
— OG7
TcCLB.504181.10 ⚠
60S ribosomal protein L9, putative
— OG7
TcCLB.511625.40 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.510291.30 ⚠
protein phosphatase 2C-like, putative
— OG7
TcCLB.506739.200 ⚠
pyruvate dehydrogenase phosphatase
— OG7
TcCLB.503989.60 ⚠
protein phosphatase 2C, putative (fragment)
— OG7
TcCLB.506925.150 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.506401.100 ⚠
DNA polymerase sigma, putative
— OG7
TcCLB.511867.170 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508995.30 ⚠
tubulin-tyrosine ligase, putative
— OG7
TcCLB.506941.80 ⚠
tubulin-tyrosine ligase-like protein, putativ
— OG7
TcCLB.510141.20 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
TcCLB.506885.270 ⚠
tubulin tyrosine ligase, putative
— OG7
TcCLB.510535.60 ⚠
ccr4-not transcription complex subunit
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.