TcCLB.506401.100

DNA polymerase sigma, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_101092 OG7: OG7_0003906 48 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 48 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.509073.90 ⚠
CS domain/TPR repeat, putative
— OG7
TcCLB.511435.49 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
TcCLB.511911.110 ⚠
RNA helicase, putative
— OG7
TcCLB.507809.100 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506223.120 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
TcCLB.509007.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.410961.10 ⚠
phosphatidylinositol kinase related protein,
— OG7
TcCLB.510075.30 ⚠
Myotubularin-related protein, putative
— OG7
TcCLB.507011.120 ⚠
acyl transferase-like protein, putative
— OG7
TcCLB.507839.9 ⚠
Myotubularin-related protein, putative (fragm
— OG7
TcCLB.510229.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510753.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506945.70 ⚠
protein mkt1, putative
— OG7
TcCLB.506885.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510029.40 ⚠
DNA-directed RNA polymerase III subunit C11,
— OG7
TcCLB.508211.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509011.20 ⚠
RNA polymerase IIA largest subunit, putative
— OG7
TcCLB.506949.10 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
TcCLB.403789.9 ⚠
DNA-directed RNA polymerase I largest subunit
— OG7
TcCLB.443683.9 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
TcCLB.504119.4 ⚠
DNA-directed RNA polymerase III subunit C1, p
— OG7
TcCLB.401473.9 ⚠
DNA-directed RNA polymerase I largest subunit
— OG7
TcCLB.508839.89 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
TcCLB.503955.70 ⚠
eukaryotic translation initiation factor 2 be
— OG7
TcCLB.508209.70 ⚠
hypothetical protein, conserved
— Both
TcCLB.508837.170 ⚠
hypothetical protein, conserved
— Both
TcCLB.508973.80 ⚠
RAVE protein 1 C terminal, putative
— Both
TcCLB.506563.20 ⚠
exosome-associated protein 1, putative
— Both
TcCLB.503453.70 ⚠
hypothetical protein, conserved
— Both
TcCLB.510771.9 ⚠
Thioredoxin-like/Protein of unknown function
— Both
TcCLB.504133.45 ⚠
Temperature dependent protein affecting M2 ds
— Both
TcCLB.510283.114 ⚠
DNA-directed RNA polymerase I subunit, putati
— Both
TcCLB.506863.70 ⚠
hypothetical protein, conserved
— Both
TcCLB.507143.70 ⚠
Galactose oxidase, central domain/Kelch motif
— Both
TcCLB.510773.9 ⚠
Thioredoxin-like/Protein of unknown function
— Both
TcCLB.509965.180
RNA-binding protein, putative
— OG6
TcCLB.506625.200 ⚠
exosome complex exonuclease, putative, riboso
— Both
TcCLB.508179.60
protein kinase, putative
— OG6
TcCLB.506147.150 ⚠
pre-RNA processing PIH1/Nop17, putative
— OG7
TcCLB.509805.170 ⚠
pre-RNA processing PIH1/Nop17, putative
— OG7
TcCLB.511621.150 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504179.40 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506779.60 ⚠
DNA-direcetd RNA polymerase II, subunit 9, pu
— OG7
TcCLB.509819.49 ⚠
Myotubularin-related protein, putative (fragm
— OG7
TcCLB.510755.19 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510431.270 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504255.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506533.34 ⚠
phosphatidylinositol kinase related protein,
— OG7
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.