TcCLB.509805.170

pre-RNA processing PIH1/Nop17, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_105060 OG7: OG7_0006226 76 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 76 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.509073.90 ⚠
CS domain/TPR repeat, putative
— Both
TcCLB.503579.30 ⚠
DNA polymerase sigma-like protein, putative
— OG7
TcCLB.401473.9 ⚠
DNA-directed RNA polymerase I largest subunit
— OG7
TcCLB.504119.4 ⚠
DNA-directed RNA polymerase III subunit C1, p
— OG7
TcCLB.443683.9 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
TcCLB.403789.9 ⚠
DNA-directed RNA polymerase I largest subunit
— OG7
TcCLB.506949.10 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
TcCLB.509011.20 ⚠
RNA polymerase IIA largest subunit, putative
— OG7
TcCLB.510073.50 ⚠
elongation factor 1-gamma (EF-1-gamma), putat
— OG7
TcCLB.506401.100 ⚠
DNA polymerase sigma, putative
— OG7
TcCLB.504227.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511753.50 ⚠
WD domain, G-beta repeat, putative
— OG7
TcCLB.511211.120 ⚠
receptor for activated C kinase 1, putative
— OG7
TcCLB.503955.70 ⚠
eukaryotic translation initiation factor 2 be
— OG7
TcCLB.509297.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511211.130 ⚠
receptor for activated C kinase 1, putative
— OG7
TcCLB.509379.10 ⚠
dihydrolipoamide dehydrogenase, putative
— OG7
TcCLB.504883.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.410961.10 ⚠
phosphatidylinositol kinase related protein,
— OG7
TcCLB.506223.120 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
TcCLB.511001.130 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506685.50 ⚠
myosin heavy chain, putative (fragment)
— OG7
TcCLB.511527.70 ⚠
Unconventional myosin
— OG7
TcCLB.507093.72 ⚠
repressor activator protein 1
— OG7
TcCLB.511365.90 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507669.70 ⚠
Dynein intermediate chain 1, axonemal
— OG7
TcCLB.503905.10 ⚠
myosin heavy chain, putative
— OG7
TcCLB.506779.190 ⚠
Unconventional myosin
— OG7
TcCLB.507445.50 ⚠
myosin heavy chain, putative
— OG7
TcCLB.504867.120 ⚠
hypothetical protein
— OG7
TcCLB.508839.89 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
TcCLB.507093.210 ⚠
myosin heavy chain, putative
— OG7
TcCLB.507795.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511131.80 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510533.170 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507811.120 ⚠
myosin heavy chain MYA2-related, putative
— OG7
TcCLB.506795.100 ⚠
hypothetical protein
— OG7
TcCLB.504103.30 ⚠
myosin heavy chain, putative
— OG7
TcCLB.511435.49 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
TcCLB.506599.10 ⚠
elongation factor 1-gamma (EF-1-gamma), putat
— Both
TcCLB.506563.30 ⚠
coatomer beta subunit, putative
— Both
TcCLB.511211.20 ⚠
Coatomer subunit gamma
— Both
TcCLB.508321.40 ⚠
Tripartite attachment complex protein 102
— Both
TcCLB.507739.110 ⚠
myosin IB heavy chain, putative
— Both
TcCLB.505945.80 ⚠
AKAP7 2'5' RNA ligase-like domain containing
— Both
TcCLB.510089.200 ⚠
Eukaryotic translation initiation factor 3 su
— Both
TcCLB.509979.40 ⚠
Zn-finger in Ran binding protein and others/S
— Both
TcCLB.507673.30 ⚠
hypothetical protein, conserved
— Both
TcCLB.507611.310 ⚠
eukaryotic translation initiation factor 3 su
— Both
TcCLB.511109.30 ⚠
dynein intermediate chain, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.