TcCLB.511753.50

WD domain, G-beta repeat, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_111964 OG7: OG7_0002697 51 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 51 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.504213.130 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511435.49 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
TcCLB.506223.120 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
TcCLB.410961.10 ⚠
phosphatidylinositol kinase related protein,
— OG7
TcCLB.503799.10 ⚠
DNA repair protein RAD50, putative
— OG7
TcCLB.503801.9 ⚠
RAD50 DNA repair protein, putative (fragment)
— OG7
TcCLB.504625.10 ⚠
trans-splicing factor, putative
— OG7
TcCLB.509379.10 ⚠
dihydrolipoamide dehydrogenase, putative
— OG7
TcCLB.507757.60 ⚠
dihydrolipoamide dehydrogenase, putative
— OG7
TcCLB.507757.70 ⚠
dihydrolipoamide dehydrogenase, putative, ace
— OG7
TcCLB.506147.150 ⚠
pre-RNA processing PIH1/Nop17, putative
— OG7
TcCLB.509805.170 ⚠
pre-RNA processing PIH1/Nop17, putative
— OG7
TcCLB.509809.10 ⚠
NADH-ubiquinone oxidoreductase complex I subu
— OG7
TcCLB.506533.34 ⚠
phosphatidylinositol kinase related protein,
— OG7
TcCLB.508089.60 ⚠
mRNA capping enzyme, beta chain, putative
— OG7
TcCLB.506825.100 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509073.90 ⚠
CS domain/TPR repeat, putative
— OG7
TcCLB.507257.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.505983.30 ⚠
general transcription factor IIB
— OG7
TcCLB.507709.120 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511369.5 ⚠
elongation factor 1-alpha, putative (fragment
— OG7
TcCLB.511369.30 ⚠
elongation factor 1-alpha, putative
— OG7
TcCLB.511369.20 ⚠
elongation factor 1-alpha, putative
— OG7
TcCLB.508949.4 ⚠
elongation factor 1-alpha (ef-1-alpha), putat
— OG7
TcCLB.508041.60 ⚠
eukaryotic release factor 3, putative
— OG7
TcCLB.511369.10 ⚠
elongation factor 1-alpha, putative
— OG7
TcCLB.503829.89 ⚠
spliceosomal U5 snRNP-specific protein, putat
— OG7
TcCLB.511423.160 ⚠
RWD domain-containing protein
— Both
TcCLB.507993.220 ⚠
ADP-ribosylation factor-like protein 2-bindin
— Both
TcCLB.509167.170 ⚠
tRNA (Guanine-1)-methyltransferase, putative
— Both
TcCLB.504153.150
Unc104-like kinesin, putative
— OG6
TcCLB.508647.20 ⚠
hypothetical protein
— OG7
TcCLB.504077.40 ⚠
translation elongation factor EF-2, putative
— OG7
TcCLB.509267.50 ⚠
U5 small nuclear ribonucleoprotein component,
— OG7
TcCLB.511217.80 ⚠
U6 snRNA-associated sm-like protein Lsm2
— OG7
TcCLB.508831.70 ⚠
U5 snRNP-specific 40 kDa protein, putative
— OG7
TcCLB.503479.49 ⚠
U6 snRNA-associated Sm-like protein LSm7p
— OG7
TcCLB.507041.40 ⚠
U5 snRNP-associated 102 kDa protein, putative
— OG7
TcCLB.508169.20 ⚠
elongation factor 2, putative
— OG7
TcCLB.510295.50
Mitogen-activated protein kinase 6
— OG6
TcCLB.510963.90 ⚠
elongation factor 2, putative
— OG7
TcCLB.506893.25 ⚠
U6 snRNA-associated Sm-like protein LSm6p
— OG7
TcCLB.508837.100 ⚠
Putative snoRNA binding domain containing pro
— OG7
TcCLB.509551.64 ⚠
small nuclear ribonucleoprotein Sm-F, putativ
— OG7
TcCLB.504643.40 ⚠
U6 snRNA-associated Sm-like protein LSm4, put
— OG7
TcCLB.510091.70 ⚠
U6 snRNA-associated Sm-like protein LSm8, put
— OG7
TcCLB.509965.30 ⚠
small nuclear ribonucleoprotein Sm-E, putativ
— OG7
TcCLB.510531.54 ⚠
small nuclear ribonucleoprotein, putative
— OG7
TcCLB.508169.9 ⚠
elongation factor 2, putative (fragment)
— OG7
TcCLB.511583.30 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.