TcCLB.506825.100

hypothetical protein, conserved
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_389798 OG7: OG7_0094280 24 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 24 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.504213.130
hypothetical protein, conserved
— Both
TcCLB.410961.10 ⚠
phosphatidylinositol kinase related protein,
— OG7
TcCLB.506223.120 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
TcCLB.506147.150 ⚠
pre-RNA processing PIH1/Nop17, putative
— OG7
TcCLB.511753.50 ⚠
WD domain, G-beta repeat, putative
— OG7
TcCLB.511435.49 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
TcCLB.506533.34 ⚠
phosphatidylinositol kinase related protein,
— OG7
TcCLB.511211.120 ⚠
receptor for activated C kinase 1, putative
— OG7
TcCLB.509379.10 ⚠
dihydrolipoamide dehydrogenase, putative
— OG7
TcCLB.511211.130 ⚠
receptor for activated C kinase 1, putative
— OG7
TcCLB.509805.170 ⚠
pre-RNA processing PIH1/Nop17, putative
— Both
TcCLB.511131.50 ⚠
U4/U6 small nuclear ribonuclear protein, puta
— Both
TcCLB.510877.60 ⚠
ruvB-like DNA helicase, putative
— Both
TcCLB.509073.90
CS domain/TPR repeat, putative
— Both
TcCLB.504625.10
trans-splicing factor, putative
— Both
TcCLB.508089.60
mRNA capping enzyme, beta chain, putative
— Both
TcCLB.507709.120
hypothetical protein, conserved
— Both
TcCLB.507757.70 ⚠
dihydrolipoamide dehydrogenase, putative, ace
— Both
TcCLB.507757.60 ⚠
dihydrolipoamide dehydrogenase, putative
— Both
TcCLB.509809.10
NADH-ubiquinone oxidoreductase complex I subu
— Both
TcCLB.509445.39 ⚠
glutamate dehydrogenase, putative
— Both
TcCLB.505843.10 ⚠
glutamate dehydrogenase, putative
— Both
TcCLB.511729.60
MORN repeat-containing protein 1
— Both
TcCLB.505989.82 ⚠
ruvB-like DNA helicase, putative
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.