TcCLB.509445.39

glutamate dehydrogenase, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_106160 OG7: OG7_0011174 112 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 112 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.504153.310 ⚠
heat shock protein, putative
— +1 more OG7
TcCLB.506591.4 ⚠
heat shock protein 90, putative
— +1 more OG7
TcCLB.503811.10 ⚠
heat shock protein 90, putative
— +1 more OG7
TcCLB.507713.30 ⚠
heat shock protein 85, putative
— +6 more Both
TcCLB.507713.40 ⚠
heat shock protein 85, putative (fragment)
— +6 more Both
TcCLB.507611.270 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510101.140 ⚠
pyruvate phosphate dikinase, putative
— Both
TcCLB.506941.130 ⚠
SET domain containing protein, putative
— Both
TcCLB.506221.70 ⚠
Paraflagellar Rod Proteome Component 9, putat
— Both
TcCLB.503953.50 ⚠
Beta-lactamase superfamily domain containing
— Both
TcCLB.506825.100 ⚠
hypothetical protein, conserved
— Both
TcCLB.507257.60 ⚠
Fumarate hydratase class I, cytosolic
— Both
TcCLB.507669.10 ⚠
fumarate hydratase, putative
— Both
TcCLB.508387.160 ⚠
Phosphatidylinositol 4-phosphate 5-kinase, pu
— Both
TcCLB.511181.80 ⚠
threonyl-tRNA synthetase, putative
— Both
TcCLB.510957.9 ⚠
calpain-like cysteine peptidase, putative
— OG6
TcCLB.506563.190 ⚠
calpain-like cysteine peptidase, putative
— OG6
TcCLB.503855.40 ⚠
calpain-like cysteine peptidase, putative, cy
— OG6
TcCLB.511311.80 ⚠
N-alpha-acetyltransferase 35, NatC auxiliary
— Both
TcCLB.506563.220 ⚠
calpain-like cysteine peptidase, putative, cy
— OG6
TcCLB.509445.10 ⚠
tryparedoxin peroxidase, putative
— Both
TcCLB.505983.9 ⚠
tryparedoxin peroxidase, putative
— Both
TcCLB.509499.14 ⚠
peroxidoxin
— Both
TcCLB.487507.10 ⚠
tryparedoxin peroxidase, putative
— Both
TcCLB.482369.10 ⚠
protein phosphatase 2A regulatory subunit, pu
— Both
TcCLB.506829.50 ⚠
Ring finger domain/Zn-finger in ubiquitin-hyd
— Both
TcCLB.503903.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507211.10 ⚠
choline/carnitine O-acyltransferase, putative
— OG7
TcCLB.511353.4 ⚠
choline/carnitine O-acyltransferase, putative
— OG7
TcCLB.511351.41 ⚠
choline/carnitine O-acyltransferase, putative
— OG7
TcCLB.503685.30 ⚠
carnitine/choline acetyltransferase, putative
— OG7
TcCLB.510749.4 ⚠
ubiquitin-protein ligase, putative
— OG7
TcCLB.507521.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503455.30 ⚠
Protein of unknown function (DUF3648), putati
— OG7
TcCLB.509965.40 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.510761.70 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.510055.70 ⚠
Kinetochore interacting protein 5, putative
— OG7
TcCLB.504009.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506465.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504125.30 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TcCLB.503975.40 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508727.44 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504133.45 ⚠
Temperature dependent protein affecting M2 ds
— OG7
TcCLB.506513.150 ⚠
WD domain, G-beta repeat, putative
— OG7
TcCLB.506239.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503905.50 ⚠
PSP1 C-terminal conserved region, putative
— OG7
TcCLB.508541.190 ⚠
cell cycle sequence binding phosphoprotein (R
— OG7
TcCLB.504103.90 ⚠
PSP1 C-terminal conserved region, putative
— OG7
TcCLB.511731.60 ⚠
glutamyl-tRNA synthetase, putative
— OG7
TcCLB.511589.200 ⚠
S-adenosylhomocysteine hydrolase, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.