TcCLB.507713.40

heat shock protein 85, putative (fragment)

Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_100204 OG7: OG7_0001978 128 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 128 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TcCLB.505843.10 ⚠ glutamate dehydrogenase, putative	—	OG6 LdBPK_151070.1 ↔ LdBPK_330360.1 OG6 TCSYLVIO_002205 ↔ TCSYLVIO_007064 OG6 TCSYLVIO_007064 ↔ TCSYLVIO_008621 OG6 TCSYLVIO_007064 ↔ TCSYLVIO_009400 +6 more	Both
TcCLB.510515.100 ⚠ coronin, putative	—	OG6 TCSYLVIO_000174 ↔ TCSYLVIO_008621 OG6 TCSYLVIO_000174 ↔ TCSYLVIO_009400 OG6 TCSYLVIO_000174 ↔ TCSYLVIO_009151 OG6 Tb927.10.10960 ↔ Tb927.8.3100 +4 more	Both
TcCLB.509445.39 ⚠ glutamate dehydrogenase, putative	—	OG6 LdBPK_151070.1 ↔ LdBPK_330360.1 OG6 TCSYLVIO_002205 ↔ TCSYLVIO_007064 OG6 TCSYLVIO_007064 ↔ TCSYLVIO_008621 OG6 TCSYLVIO_007064 ↔ TCSYLVIO_009400 +6 more	Both
TcCLB.503811.10 ⚠ heat shock protein 90, putative	—	OG7 LdBPK_290790.1 ↔ LdBPK_330360.1 OG7 TCSYLVIO_002205 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_008593 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_009151 ↔ TCSYLVIO_009400 +4 more	OG7
TcCLB.511217.200 ⚠ tyrosyl or methionyl-tRNA synthetase, putativ	—	OG6 LdBPK_161170.1 ↔ LdBPK_330360.1 OG7 TCSYLVIO_001244 ↔ TCSYLVIO_005578 OG7 LdBPK_161170.1 ↔ LdBPK_330360.1	Both
TcCLB.508321.50 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_161170.1 ↔ LdBPK_330360.1 OG7 TCSYLVIO_001244 ↔ TCSYLVIO_005578 OG7 LdBPK_161170.1 ↔ LdBPK_330360.1	Both
TcCLB.506591.4 ⚠ heat shock protein 90, putative	—	OG7 LdBPK_290790.1 ↔ LdBPK_330360.1 OG7 TCSYLVIO_002205 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_008593 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_009151 ↔ TCSYLVIO_009400 +4 more	OG7
TcCLB.504153.310 ⚠ heat shock protein, putative	—	OG7 LdBPK_290790.1 ↔ LdBPK_330360.1 OG7 TCSYLVIO_002205 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_008593 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_009151 ↔ TCSYLVIO_009400 +4 more	OG7
TcCLB.507713.30 ⚠ heat shock protein 85, putative	—	OG6 LdBPK_290790.1 ↔ LdBPK_330360.1 OG6 TCSYLVIO_002205 ↔ TCSYLVIO_008621 OG6 TCSYLVIO_008593 ↔ TCSYLVIO_008621 OG6 TCSYLVIO_009151 ↔ TCSYLVIO_009400 +12 more	Both
TcCLB.507809.110 ⚠ WD domain, G-beta repeat, putative	—	OG6 TCSYLVIO_009151 ↔ TCSYLVIO_010560 OG6 TCSYLVIO_009400 ↔ TCSYLVIO_010560 OG6 TCSYLVIO_008621 ↔ TCSYLVIO_010560 OG7 Tb927.3.3580 ↔ Tb927.5.3260 +3 more	Both
TcCLB.509157.90 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_004111 ↔ TCSYLVIO_011092	OG7
TcCLB.510743.100 ⚠ chaperone DNAJ protein, putative	—	OG7 TCSYLVIO_003497 ↔ TCSYLVIO_005578	OG7
TcCLB.508179.10 ⚠ DnaJ chaperone protein, putative	—	OG7 TCSYLVIO_003497 ↔ TCSYLVIO_005578	OG7
TcCLB.510165.10 ⚠ heat shock protein DNAJ, putative	—	OG7 TCSYLVIO_003497 ↔ TCSYLVIO_005578	OG7
TcCLB.511531.9 ⚠ chaperone DNAJ protein, putative	—	OG7 TCSYLVIO_003497 ↔ TCSYLVIO_005578	OG7
TcCLB.507257.180 ⚠ hypothetical protein	—	OG7 TCSYLVIO_003497 ↔ TCSYLVIO_005578	OG7
TcCLB.511627.110 ⚠ heat shock protein DNAJ, putative	—	OG7 TCSYLVIO_003497 ↔ TCSYLVIO_005578	OG7
TcCLB.506777.60 ⚠ NGG1 interacting factor 3, putative	—	OG7 TCSYLVIO_001715 ↔ TCSYLVIO_005578	OG7
TcCLB.503479.70 ⚠ hook complex protein, conserved	—	OG7 TCSYLVIO_005619 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_005619 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_005619 ↔ TCSYLVIO_009151	OG7
TcCLB.510751.10 ⚠ poly(A)-specific ribonuclease PARN, putative	—	OG7 TCSYLVIO_000055 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_000055 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_000055 ↔ TCSYLVIO_009151	OG7
TcCLB.506265.70 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_007569 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_007569 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_007569 ↔ TCSYLVIO_009151	OG7
TcCLB.486901.10 ⚠ endonuclease/exonuclease/phosphatase, putativ	—	OG7 TCSYLVIO_007569 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_007569 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_007569 ↔ TCSYLVIO_009151	OG7
TcCLB.506147.30 ⚠ synaptojanin (N-terminal domain), putative, i	—	OG7 TCSYLVIO_007569 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_007569 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_007569 ↔ TCSYLVIO_009151	OG7
TcCLB.510765.70 ⚠ 60S ribosomal protein L5, putative	—	OG7 TCSYLVIO_001078 ↔ TCSYLVIO_010666	OG7
TcCLB.510765.60 ⚠ 60S ribosomal protein L5, putative	—	OG7 TCSYLVIO_001078 ↔ TCSYLVIO_010666	OG7
TcCLB.509979.100 ⚠ WD domain, G-beta repeat, putative	—	OG7 TCSYLVIO_005180 ↔ TCSYLVIO_005578	OG7
TcCLB.504009.10 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_330360.1 ↔ LdBPK_331280.1	OG7
TcCLB.511181.90 ⚠ peroxisome targeting signal 1 receptor, putat	—	OG7 TCSYLVIO_005361 ↔ TCSYLVIO_005578	OG7
TcCLB.504137.10 ⚠ isoleucyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005578	OG7
TcCLB.511911.21 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_003867 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_009151 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_005578	OG7
TcCLB.510777.20 ⚠ aspartyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_003867 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_009151 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_005578	OG7
TcCLB.510749.40 ⚠ cysteine peptidase, Clan CA, family C19, puta	—	OG7 TCSYLVIO_005374 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_005374 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_005374 ↔ TCSYLVIO_009151	OG7
TcCLB.508357.40 ⚠ ubiquitin carboxyl-terminal hydrolase, putati	—	OG7 TCSYLVIO_005374 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_005374 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_005374 ↔ TCSYLVIO_009151	OG7
TcCLB.509967.30 ⚠ aspartyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_003867 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_009151 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_005578	OG7
TcCLB.511581.10 ⚠ fatty acyl CoA synthetase 2, putative	—	OG7 TCSYLVIO_003436 ↔ TCSYLVIO_010666	OG7
TcCLB.506829.110 ⚠ fatty acyl CoA synthetase 2, putative	—	OG7 TCSYLVIO_003436 ↔ TCSYLVIO_010666	OG7
TcCLB.511581.20 ⚠ fatty acyl CoA syntetase 1 (fragment)	—	OG7 TCSYLVIO_003436 ↔ TCSYLVIO_010666	OG7
TcCLB.509247.50 ⚠ methionyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_005578 ↔ TCSYLVIO_007991	OG7
TcCLB.506363.70 ⚠ amidohydrolase, putative	—	OG7 TCSYLVIO_005578 ↔ TCSYLVIO_008414	OG7
TcCLB.506795.80 ⚠ B-cell mitogen precursor, putative, proline r	—	OG7 TCSYLVIO_005578 ↔ TCSYLVIO_010607	OG7
TcCLB.506363.80 ⚠ N-acyl-L-amino acid amidohydrolase, putative,	—	OG7 TCSYLVIO_005578 ↔ TCSYLVIO_008414	OG7
TcCLB.511585.130 ⚠ ubiquitin activating enzyme, putative	—	OG7 TCSYLVIO_009151 ↔ TCSYLVIO_010542 OG7 TCSYLVIO_009400 ↔ TCSYLVIO_010542 OG7 TCSYLVIO_008621 ↔ TCSYLVIO_010542	OG7
TcCLB.508089.30 ⚠ N-terminal conserved domain of Nudc./CS domai	—	OG7 TCSYLVIO_005578 ↔ TCSYLVIO_010327	OG7
TcCLB.510407.90 ⚠ serine hydroxymethyltransferase, putative	—	OG7 TCSYLVIO_005578 ↔ TCSYLVIO_010621	OG7
TcCLB.510719.310 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_005578 ↔ TCSYLVIO_008197	OG7
TcCLB.507929.20 ⚠ co-chaperone GrpE, putative	—	OG7 TCSYLVIO_003139 ↔ TCSYLVIO_005578	OG7
TcCLB.506673.60 ⚠ Adaptor protein complex AP-3 subunit beta-3	—	OG7 TCSYLVIO_004597 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_004597 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_004597 ↔ TCSYLVIO_009151	OG7
TcCLB.510101.150 ⚠ adaptin-related protein-like, putative	—	OG7 TCSYLVIO_004597 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_004597 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_004597 ↔ TCSYLVIO_009151	OG7
TcCLB.504137.60 ⚠ beta adaptin, putative	—	OG7 TCSYLVIO_004597 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_004597 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_004597 ↔ TCSYLVIO_009151	OG7
TcCLB.510999.10 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_005083 ↔ TCSYLVIO_005578	OG7

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