TcCLB.504153.310

heat shock protein, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_103348 OG7: OG7_0001978 122 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 122 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.507809.110 ⚠
WD domain, G-beta repeat, putative
— OG7
TcCLB.507713.30 ⚠
heat shock protein 85, putative
— +4 more OG7
TcCLB.510515.100 ⚠
coronin, putative
— OG7
TcCLB.506591.4 ⚠
heat shock protein 90, putative
— +4 more OG7
TcCLB.503811.10 ⚠
heat shock protein 90, putative
— +4 more OG7
TcCLB.507713.40 ⚠
heat shock protein 85, putative (fragment)
— +4 more OG7
TcCLB.511217.200 ⚠
tyrosyl or methionyl-tRNA synthetase, putativ
— Both
TcCLB.508321.50 ⚠
hypothetical protein, conserved
— Both
TcCLB.505843.10 ⚠
glutamate dehydrogenase, putative
— +1 more OG7
TcCLB.509445.39 ⚠
glutamate dehydrogenase, putative
— +1 more OG7
TcCLB.506773.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509073.30 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.503885.90 ⚠
WD domain, G-beta repeat/PFU (PLAA family ubi
— OG7
TcCLB.510749.40 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
TcCLB.508357.40 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TcCLB.506221.70 ⚠
Paraflagellar Rod Proteome Component 9, putat
— OG7
TcCLB.511581.10 ⚠
fatty acyl CoA synthetase 2, putative
— OG7
TcCLB.506829.110 ⚠
fatty acyl CoA synthetase 2, putative
— OG7
TcCLB.511001.190 ⚠
vacuolar ATP synthase subunit d, putative
— OG7
TcCLB.511581.20 ⚠
fatty acyl CoA syntetase 1 (fragment)
— OG7
TcCLB.506829.100 ⚠
fatty acyl CoA syntetase 1, putative
— OG7
TcCLB.511579.9 ⚠
fatty acyl CoA syntetase 1, putative (fragmen
— OG7
TcCLB.503575.50 ⚠
fatty acyl CoA synthetase, putative
— OG7
TcCLB.503613.60 ⚠
acidocalcisomal pyrophosphatase, putative
— OG7
TcCLB.508181.140 ⚠
inorganic pyrophosphatase, putative
— OG7
TcCLB.509157.90 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506127.30 ⚠
phenylalanyl-tRNA synthetase, putative
— OG7
TcCLB.508271.10 ⚠
phenylalanyl-tRNA synthetase, putative
— OG7
TcCLB.511571.40 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511555.60 ⚠
ubiquitin ligase, putative
— OG7
TcCLB.511537.69 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511539.9 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503637.30 ⚠
serine peptidase, Clan SC, Family S9B
— OG7
TcCLB.505983.20 ⚠
nucleosome assembly protein-like protein, put
— +1 more OG7
TcCLB.509455.80 ⚠
GTP-binding nuclear protein rtb2, putative
— OG7
TcCLB.506363.80 ⚠
N-acyl-L-amino acid amidohydrolase, putative,
— OG7
TcCLB.506635.70 ⚠
Zeta toxin, putative
— OG7
TcCLB.511575.40 ⚠
exonuclease, putative
— OG7
TcCLB.511585.130 ⚠
ubiquitin activating enzyme, putative
— OG7
TcCLB.511145.60 ⚠
ATP synthase F1 subunit gamma protein, putati
— OG7
TcCLB.510351.90 ⚠
dihydrolipoamide branched chain transacylase,
— OG7
TcCLB.503801.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511067.10 ⚠
tubulin folding cofactor D, putative
— OG7
TcCLB.510407.90 ⚠
serine hydroxymethyltransferase, putative
— Both
TcCLB.510101.150 ⚠
adaptin-related protein-like, putative
— OG7
TcCLB.504137.60 ⚠
beta adaptin, putative
— OG7
TcCLB.503689.40 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508347.120 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509761.10 ⚠
Metallopeptidase family M24/FACT complex subu
— OG7
TcCLB.503589.10 ⚠
GDP-mannose pyrophosphorylase
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.