TcCLB.503637.30

serine peptidase, Clan SC, Family S9B
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_102236 OG7: OG7_0002160 170 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 170 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.510751.10 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
TcCLB.504137.10
isoleucyl-tRNA synthetase, putative
— Both
TcCLB.506777.60
NGG1 interacting factor 3, putative
— Both
TcCLB.506885.413 ⚠
glyceraldehyde-3-phosphate dehydrogenase, put
— Both
TcCLB.510911.50 ⚠
glycine cleavage system P-protein, putative,
— Both
TcCLB.422507.10 ⚠
glycine dehydrogenase [decarboxylating], puta
— Both
TcCLB.506351.80 ⚠
serine peptidase, clan SC, family S9A-like pr
— Both
TcCLB.511557.10 ⚠
oligopeptidase b
— Both
TcCLB.510321.20 ⚠
NOL1/NOP2/sun family, putative
— Both
TcCLB.506699.3 ⚠
NOL1/NOP2/sun family, putative
— Both
TcCLB.511555.60
ubiquitin ligase, putative
— Both
TcCLB.511067.10
tubulin folding cofactor D, putative
— Both
TcCLB.509757.30 ⚠
stress-inducible protein STI1-like, putative
— Both
TcCLB.511627.100 ⚠
TPR-repeat protein, putative
— Both
TcCLB.506863.10
alanyl-tRNA synthetase, putative
— Both
TcCLB.509595.50 ⚠
DIS3-like exonuclease, putative
— Both
TcCLB.504427.200 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
TcCLB.506251.100 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
TcCLB.429257.10
Gar1/Naf1 RNA binding region, putative
— Both
TcCLB.508347.120 ⚠
hypothetical protein, conserved
— Both
TcCLB.503689.40 ⚠
hypothetical protein, conserved
— Both
TcCLB.508181.140 ⚠
inorganic pyrophosphatase, putative
— Both
TcCLB.503613.60 ⚠
acidocalcisomal pyrophosphatase, putative
— Both
TcCLB.511001.190
vacuolar ATP synthase subunit d, putative
— Both
TcCLB.504153.140
metallo-peptidase, Clan MF, Family M17
— OG7
TcCLB.508241.120 ⚠
rrp44p homologue, putative
— OG7
TcCLB.506287.30 ⚠
cytochrome b5-like Heme/Steroid binding domai
— OG7
TcCLB.506773.44 ⚠
cytochrome b5, putative
— OG7
TcCLB.507047.160 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506753.110 ⚠
cytochrome b5-like protein, putative
— OG7
TcCLB.504431.109 ⚠
cytochrome b5, putative
— OG7
TcCLB.503653.60 ⚠
cytochrome b-domain protein, putative
— OG7
TcCLB.461165.16 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG7
TcCLB.506943.50 ⚠
glyceraldehyde 3-phosphate dehydrogenase, put
— OG7
TcCLB.508537.10 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG7
TcCLB.510105.230 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG7
TcCLB.506943.60 ⚠
glyceraldehyde 3-phosphate dehydrogenase, put
— OG7
TcCLB.506409.240 ⚠
glyceraldehyde 3-phosphate dehydrogenase, C-t
— OG7
TcCLB.510963.50 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
TcCLB.508181.20 ⚠
6-phosphofructo-2-kinase 1
— OG7
TcCLB.508569.130 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
TcCLB.504867.20
ABC transporter, putative
— OG7
TcCLB.503479.70 ⚠
hook complex protein, conserved
— OG7
TcCLB.506147.30 ⚠
synaptojanin (N-terminal domain), putative, i
— OG7
TcCLB.506885.320 ⚠
TPR repeat/Tetratricopeptide repeat, putative
— OG7
TcCLB.509381.10 ⚠
mitochondrial import receptor subunit, putati
— OG7
TcCLB.509537.80 ⚠
TPR repeat, putative
— OG7
TcCLB.507669.160 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506375.10 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
TcCLB.506591.4 ⚠
heat shock protein 90, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.