TcCLB.506943.50

glyceraldehyde 3-phosphate dehydrogenase, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_100218 OG7: OG7_0002325 75 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 75 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.506529.430 ⚠
alanine aminotransferase, putative, glutamic-
— Both
TcCLB.503749.10 ⚠
Serine hydrolase (FSH1)/RWD domain/50S riboso
— OG7
TcCLB.509099.10 ⚠
GTP-binding protein, putative
— OG7
TcCLB.509007.40 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503637.30 ⚠
serine peptidase, Clan SC, Family S9B
— OG7
TcCLB.507993.390 ⚠
pyruvate kinase 2, putative
— Both
TcCLB.506529.508 ⚠
glucose-6-phosphate isomerase, glycosomal, pu
— Both
TcCLB.511351.9 ⚠
inosine-5'-monophosphate dehydrogenase, putat
— Both
TcCLB.507211.40 ⚠
inosine-5'-monophosphate dehydrogenase, putat
— Both
TcCLB.506519.130 ⚠
GMP reductase
— OG6
TcCLB.511625.50 ⚠
GTP-binding protein, putative
— OG7
TcCLB.506529.420 ⚠
glutamic--pyruvic transaminase, putative, ala
— Both
TcCLB.506933.60 ⚠
mitochondrial RNA binding protein, putative
— Both
TcCLB.507639.20 ⚠
universal minicircle sequence binding protein
— Both
TcCLB.507639.30 ⚠
universal minicircle sequence binding protein
— Both
TcCLB.507639.10 ⚠
poly-zinc finger protein 2, putative
— OG6
TcCLB.507511.40 ⚠
G5-interacting protein, putative
— Both
TcCLB.506409.240 ⚠
glyceraldehyde 3-phosphate dehydrogenase, C-t
— Both
TcCLB.503575.50 ⚠
fatty acyl CoA synthetase, putative
— Both
TcCLB.506367.10 ⚠
isovaleryl-coA dehydrogenase, putative (fragm
— OG7
TcCLB.510027.10 ⚠
GDP-mannose 4,6 dehydratase, putative
— OG7
TcCLB.506375.10 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
TcCLB.506375.60 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
TcCLB.508277.150 ⚠
proliferative cell nuclear antigen (PCNA), pu
— OG7
TcCLB.511445.100 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508277.360 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.510761.70 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.507257.70 ⚠
protein farnesyltransferase alpha subunit, pu
— OG7
TcCLB.506777.60 ⚠
NGG1 interacting factor 3, putative
— OG7
TcCLB.506943.60 ⚠
glyceraldehyde 3-phosphate dehydrogenase, put
— Both
TcCLB.509829.20 ⚠
isovaleryl-coA dehydrogenase, putative
— OG7
TcCLB.511211.220 ⚠
heat shock protein 70, putative
— OG7
TcCLB.422507.10 ⚠
glycine dehydrogenase [decarboxylating], puta
— OG7
TcCLB.511731.60 ⚠
glutamyl-tRNA synthetase, putative
— OG7
TcCLB.510911.50 ⚠
glycine cleavage system P-protein, putative,
— OG7
TcCLB.507811.114 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511751.30 ⚠
queuine tRNA-ribosyltransferase, putative
— OG7
TcCLB.509767.120 ⚠
GAF domain/TIP41-like family, putative
— OG7
TcCLB.503405.10 ⚠
glutamine synthetase
— Both
TcCLB.507669.10 ⚠
fumarate hydratase, putative
— Both
TcCLB.505983.9 ⚠
tryparedoxin peroxidase, putative
— Both
TcCLB.511579.9 ⚠
fatty acyl CoA syntetase 1, putative (fragmen
— Both
TcCLB.510259.50 ⚠
21 kDa cyclophilin, putative, PPIase, putativ
— OG6
TcCLB.506885.413 ⚠
glyceraldehyde-3-phosphate dehydrogenase, put
— Both
TcCLB.507257.60 ⚠
Fumarate hydratase class I, cytosolic
— Both
TcCLB.509445.10 ⚠
tryparedoxin peroxidase, putative
— Both
TcCLB.506649.70 ⚠
fructose-1,6-bisphosphatase, cytosolic, putat
— Both
TcCLB.509499.10 ⚠
cyclophilin, putative, peptidyl-prolyl cis-tr
— OG6
TcCLB.509499.14 ⚠
peroxidoxin
— Both
TcCLB.508207.180 ⚠
Eukaryotic translation initiation factor 4E t
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.