TcCLB.509099.10

GTP-binding protein, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_142919 OG7: OG7_0003363 50 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 50 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.511041.4 ⚠
Sucrase/ferredoxin-like, putative
— OG7
TcCLB.503955.20 ⚠
mitochondrial DNA polymerase beta, putative
— OG7
TcCLB.508357.100 ⚠
Serine-threonine kinase receptor-associated p
— OG7
TcCLB.511545.120 ⚠
superoxide dismutase, putative
— OG7
TcCLB.507739.90 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509775.40 ⚠
iron superoxide dismutase A, mitochondrial
— OG7
TcCLB.504017.79 ⚠
glycyl-tRNA synthetase, putative
— OG7
TcCLB.510761.70 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.503697.110 ⚠
Soluble NSF attachment protein, SNAP, putativ
— OG7
TcCLB.506503.160 ⚠
CYTH domain containing protein, putative
— OG7
TcCLB.510105.230 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG7
TcCLB.508085.10 ⚠
GMP synthase, putative
— OG7
TcCLB.506779.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503405.10 ⚠
glutamine synthetase
— OG7
TcCLB.511215.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503425.20 ⚠
monothiol glutaredoxin, putative
— OG7
TcCLB.506943.60 ⚠
glyceraldehyde 3-phosphate dehydrogenase, put
— OG7
TcCLB.508277.360 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.506925.350 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511179.100 ⚠
monothiol glutaredoxin, putative
— OG7
TcCLB.504147.30 ⚠
Protein of unknown function (DUF2870), putati
— OG7
TcCLB.506409.240 ⚠
glyceraldehyde 3-phosphate dehydrogenase, C-t
— OG7
TcCLB.506945.40 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511621.220 ⚠
esterase, putative
— OG7
TcCLB.511621.90 ⚠
esterase, putative
— OG7
TcCLB.507039.10 ⚠
iron superoxide dismutase, putative
— OG7
TcCLB.510027.10 ⚠
GDP-mannose 4,6 dehydratase, putative
— Both
TcCLB.507993.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508207.240 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic, p
— OG7
TcCLB.461165.16 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG7
TcCLB.506943.50 ⚠
glyceraldehyde 3-phosphate dehydrogenase, put
— OG7
TcCLB.511589.230 ⚠
eukaryotic translation initiation factor 3 su
— OG7
TcCLB.506405.10 ⚠
phosphomannomutase-like protein, putative
— OG7
TcCLB.508537.10 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG7
TcCLB.506811.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503955.10 ⚠
mitochondrial DNA polymerase beta-PAK, putati
— OG7
TcCLB.506147.100 ⚠
Spindle assembly abnormal protein 6 homolog
— OG7
TcCLB.503953.59 ⚠
mitochondrial DNA polymerase beta-PAK, putati
— OG7
TcCLB.506885.413 ⚠
glyceraldehyde-3-phosphate dehydrogenase, put
— Both
TcCLB.506893.80 ⚠
monothiol glutaredoxin, putative
— OG7
TcCLB.511303.34 ⚠
Macro domain containing protein, putative
— OG7
TcCLB.506947.70 ⚠
2OG-Fe(II) oxygenase superfamily, putative
— OG7
TcCLB.503589.10 ⚠
GDP-mannose pyrophosphorylase
— OG7
TcCLB.504159.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511711.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511589.260 ⚠
glycyl-tRNA synthetase, putative
— OG7
TcCLB.507603.30 ⚠
PITH domain-containing protein
— OG7
TcCLB.511715.10 ⚠
iron superoxide dismutase, putative
— OG7
TcCLB.508729.18 ⚠
Sucrase/ferredoxin-like, putative
— OG7
TcCLB.507089.100 ⚠
hypothetical protein, conserved
— OG7
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.