TcCLB.506811.20

hypothetical protein, conserved
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_157138 OG7: OG7_0023961 54 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 54 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.509381.10 ⚠
mitochondrial import receptor subunit, putati
— OG7
TcCLB.506411.10 ⚠
metallo-peptidase, clan MA(E), family M3, put
— OG7
TcCLB.508127.5 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508357.100 ⚠
Serine-threonine kinase receptor-associated p
— OG7
TcCLB.511545.120 ⚠
superoxide dismutase, putative
— OG7
TcCLB.504147.80 ⚠
mitochondrial intermediate peptidase, putativ
— OG7
TcCLB.509775.40 ⚠
iron superoxide dismutase A, mitochondrial
— OG7
TcCLB.503697.110 ⚠
Soluble NSF attachment protein, SNAP, putativ
— OG7
TcCLB.511041.4 ⚠
Sucrase/ferredoxin-like, putative
— OG7
TcCLB.503425.20 ⚠
monothiol glutaredoxin, putative
— OG7
TcCLB.511179.100 ⚠
monothiol glutaredoxin, putative
— OG7
TcCLB.504147.30 ⚠
Protein of unknown function (DUF2870), putati
— OG7
TcCLB.507669.160 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509537.80 ⚠
TPR repeat, putative
— OG7
TcCLB.507047.120 ⚠
myo-inositol-1(or 4)-monophosphatase 1, putat
— OG7
TcCLB.506885.320 ⚠
TPR repeat/Tetratricopeptide repeat, putative
— OG7
TcCLB.509127.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511737.10 ⚠
small glutamine-rich tetratricopeptide repeat
— OG7
TcCLB.504153.300 ⚠
GTPase protein, putative
— OG7
TcCLB.506287.150 ⚠
GTP-binding protein, putative
— OG7
TcCLB.510351.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510609.30 ⚠
GTPase, putative
— OG7
TcCLB.507689.50 ⚠
metallo-peptidase, clan MH, family M18, putat
— OG7
TcCLB.507689.40 ⚠
metallo-peptidase, clan MH, family M18, putat
— OG7
TcCLB.507689.30 ⚠
metallo-peptidase, clan MH, family M18, putat
— OG7
TcCLB.506947.70 ⚠
2OG-Fe(II) oxygenase superfamily, putative
— OG7
TcCLB.508207.240 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic, p
— OG7
TcCLB.507993.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.484299.10 ⚠
trypanothione reductase, putative
— Both
TcCLB.509757.30 ⚠
stress-inducible protein STI1-like, putative
— Both
TcCLB.511627.100 ⚠
TPR-repeat protein, putative
— Both
TcCLB.506779.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509099.10 ⚠
GTP-binding protein, putative
— OG7
TcCLB.503749.10 ⚠
Serine hydrolase (FSH1)/RWD domain/50S riboso
— OG7
TcCLB.511625.50 ⚠
GTP-binding protein, putative
— OG7
TcCLB.511621.220 ⚠
esterase, putative
— OG7
TcCLB.511621.90 ⚠
esterase, putative
— OG7
TcCLB.506931.10 ⚠
haloacid dehalogenase-like hydrolase, putativ
— OG7
TcCLB.506779.170 ⚠
haloacid dehalogenase hydrolase, putative
— OG7
TcCLB.511215.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508085.10 ⚠
GMP synthase, putative
— OG7
TcCLB.504507.5 ⚠
trypanothione reductase, putative (fragment)
— Both
TcCLB.511589.230 ⚠
eukaryotic translation initiation factor 3 su
— OG7
TcCLB.506405.10 ⚠
phosphomannomutase-like protein, putative
— OG7
TcCLB.506147.100 ⚠
Spindle assembly abnormal protein 6 homolog
— OG7
TcCLB.507039.10 ⚠
iron superoxide dismutase, putative
— OG7
TcCLB.506893.80 ⚠
monothiol glutaredoxin, putative
— OG7
TcCLB.511303.34 ⚠
Macro domain containing protein, putative
— OG7
TcCLB.506579.30 ⚠
myo-inositol-1 phosphatase, putative
— OG7
TcCLB.504159.70 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.