TcCLB.507993.60

hypothetical protein, conserved
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_101308 OG7: OG7_0003431 158 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 158 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.506493.50 ⚠
CAMK/CAMKL pseudokinase, putative
— OG7
TcCLB.503989.60 ⚠
protein phosphatase 2C, putative (fragment)
— OG7
TcCLB.511589.140 ⚠
PEP mutase, putative, phosphoenolpyruvate mut
— OG7
TcCLB.509455.30 ⚠
TAP42-like family, putative
— OG7
TcCLB.507165.59 ⚠
Protein of unknown function (DUF2009), putati
— OG7
TcCLB.507993.390 ⚠
pyruvate kinase 2, putative
— OG7
TcCLB.509979.40 ⚠
Zn-finger in Ran binding protein and others/S
— OG7
TcCLB.511303.40 ⚠
carnitine O-acetyltransferase, putative
— OG7
TcCLB.506885.320 ⚠
TPR repeat/Tetratricopeptide repeat, putative
— OG7
TcCLB.506925.319 ⚠
isocitrate dehydrogenase, putative
— OG7
TcCLB.506739.200 ⚠
pyruvate dehydrogenase phosphatase
— OG7
TcCLB.506495.3 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507211.10 ⚠
choline/carnitine O-acyltransferase, putative
— OG7
TcCLB.503959.78 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509127.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510291.30 ⚠
protein phosphatase 2C-like, putative
— OG7
TcCLB.510143.40 ⚠
UBX domain-containing protein
— OG7
TcCLB.503991.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506407.60 ⚠
CS domain containing protein, putative
— OG7
TcCLB.510311.90 ⚠
quinone oxidoreductase, putative
— OG7
TcCLB.511627.100 ⚠
TPR-repeat protein, putative
— OG7
TcCLB.464807.10 ⚠
serine/threonine protein kinase, putative, CA
— OG7
TcCLB.511145.80 ⚠
RNA polymerase II, putative
— OG7
TcCLB.507993.330 ⚠
mevalonate-diphosphate decarboxylase, putativ
— OG7
TcCLB.511353.4 ⚠
choline/carnitine O-acyltransferase, putative
— OG7
TcCLB.511351.41 ⚠
choline/carnitine O-acyltransferase, putative
— OG7
TcCLB.507809.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510939.9 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511801.14 ⚠
protein lipid droplet kinase (LDK)
— OG7
TcCLB.511353.40 ⚠
eukaryotic translation initiation factor 4E (
— OG7
TcCLB.511575.60 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— OG7
TcCLB.511737.10 ⚠
small glutamine-rich tetratricopeptide repeat
— OG7
TcCLB.508373.20 ⚠
dihydroorotase, putative
— OG7
TcCLB.506591.20 ⚠
U-box domain protein, putative
— OG7
TcCLB.507993.150 ⚠
Activator of Hsp90 ATPase, N-terminal/Activat
— OG7
TcCLB.508955.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506525.80 ⚠
N-myristoyl transferase, putative
— OG7
TcCLB.503685.30 ⚠
carnitine/choline acetyltransferase, putative
— OG7
TcCLB.511001.60 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
TcCLB.511625.40 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.510611.79 ⚠
Present in the outer mitochondrial membrane p
— OG7
TcCLB.506811.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508347.130 ⚠
deoxyhypusine hydroxylase, putative
— OG7
TcCLB.508383.10 ⚠
Present in the outer mitochondrial membrane p
— OG7
TcCLB.509965.330 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510755.65 ⚠
hypothetical protein
— OG7
TcCLB.505807.180 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— OG7
TcCLB.511871.40 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
TcCLB.506949.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511801.50 ⚠
tRNA threonylcarbamoyl adenosine modification
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.