TcCLB.509965.330

hypothetical protein, conserved
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_105186 OG7: OG7_0009787 191 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 191 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.511305.10 ⚠
5'-3' exoribonuclease B, putative
— OG7
TcCLB.508955.20 ⚠
hypothetical protein, conserved
— Both
TcCLB.509013.19 ⚠
calpain-like cysteine peptidase, putative (fr
— Both
TcCLB.503685.30 ⚠
carnitine/choline acetyltransferase, putative
— Both
TcCLB.511625.40 ⚠
protein phosphatase 2C, putative
— Both
TcCLB.507941.100 ⚠
hypothetical protein, conserved
— Both
TcCLB.504147.30 ⚠
Protein of unknown function (DUF2870), putati
— Both
TcCLB.509551.70 ⚠
Co-chaperone protein P23
— Both
TcCLB.509453.4 ⚠
hypothetical protein, conserved
— Both
TcCLB.509013.10 ⚠
calpain-like cysteine peptidase, putative
— Both
TcCLB.507795.100 ⚠
mitochondrial ribosomal protein L3, putative
— Both
TcCLB.506625.160 ⚠
hypothetical protein, conserved
— Both
TcCLB.506949.20 ⚠
hypothetical protein, conserved
— Both
TcCLB.504125.60 ⚠
Kinesin-13 3, putative
— Both
TcCLB.507585.10 ⚠
amino acid transporter, putative
— OG6
TcCLB.511741.50 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic, p
— OG6
TcCLB.511543.30 ⚠
amino acid permease, putative, amino acid tra
— OG6
TcCLB.508207.240 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic, p
— Both
TcCLB.506227.110 ⚠
Mitochondrial large ribosomal subunit mL52, p
— Both
TcCLB.506227.120 ⚠
hypothetical protein, conserved
— Both
TcCLB.508085.10 ⚠
GMP synthase, putative
— Both
TcCLB.503477.20 ⚠
transaldolase, putative
— Both
TcCLB.407477.60 ⚠
hypothetical protein, conserved
— Both
TcCLB.510025.170 ⚠
mucin TcMUCII, putative
— OG6
TcCLB.507817.80 ⚠
5'-3' exoribonuclease A, putative (fragment)
— Both
TcCLB.506351.9 ⚠
5'-3' exoribonuclease A, putative (fragment)
— Both
TcCLB.507641.80 ⚠
5'-3' exoribonuclease D, putative
— Both
TcCLB.506947.100 ⚠
Mitochondrial large ribosomal subunit uL15m,
— Both
TcCLB.508323.110 ⚠
Mitochondrial large ribosomal subunit mL71, p
— Both
TcCLB.510517.30 ⚠
hypothetical protein, conserved
— Both
TcCLB.511693.70 ⚠
hypothetical protein, conserved
— Both
TcCLB.509767.90 ⚠
alanine racemase, putative
— Both
TcCLB.511693.90 ⚠
electron-transfer-flavoprotein, alpha polypep
— Both
TcCLB.506931.10 ⚠
haloacid dehalogenase-like hydrolase, putativ
— Both
TcCLB.503841.70 ⚠
aspartate aminotransferase, putative
— Both
TcCLB.509955.10 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— Both
TcCLB.509953.9 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— Both
TcCLB.508207.200 ⚠
small GTP-binding protein, putative
— Both
TcCLB.504149.140 ⚠
hypothetical protein, conserved
— Both
TcCLB.511115.40 ⚠
transcription elongation factor s-II, putativ
— Both
TcCLB.511801.50 ⚠
tRNA threonylcarbamoyl adenosine modification
— Both
TcCLB.506895.40 ⚠
Kinesin-13 1, putative
— OG7
TcCLB.509589.30 ⚠
Kinesin-13 5, putative
— OG7
TcCLB.508921.30 ⚠
Kinesin-13 4, putative
— OG7
TcCLB.505123.28 ⚠
Kinesin-13 4, putative
— OG7
TcCLB.510841.10 ⚠
Kinesin-13 4b, putative (fragment)
— OG7
TcCLB.511627.120 ⚠
aldo/keto reductase, putative
— OG7
TcCLB.506779.170 ⚠
haloacid dehalogenase hydrolase, putative
— OG7
TcCLB.511351.41 ⚠
choline/carnitine O-acyltransferase, putative
— OG7
TcCLB.510351.70 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.