TcCLB.508955.20

hypothetical protein, conserved
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_157104 OG7: OG7_0033971 221 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 221 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.511351.41 ⚠
choline/carnitine O-acyltransferase, putative
— OG7
TcCLB.510997.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511307.6 ⚠
NOL1/NOP2/sun family, putative
— OG7
TcCLB.506699.3 ⚠
NOL1/NOP2/sun family, putative
— OG7
TcCLB.509805.40 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— OG7
TcCLB.510321.20 ⚠
NOL1/NOP2/sun family, putative
— OG7
TcCLB.509123.30 ⚠
kinetoplast polyadenylation/uridylation facto
— OG7
TcCLB.508463.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.399033.19 ⚠
kinetoplast polyadenylation/uridylation facto
— OG7
TcCLB.509551.140 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511737.10 ⚠
small glutamine-rich tetratricopeptide repeat
— OG7
TcCLB.509127.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506885.320 ⚠
TPR repeat/Tetratricopeptide repeat, putative
— OG7
TcCLB.509381.10 ⚠
mitochondrial import receptor subunit, putati
— OG7
TcCLB.509537.80 ⚠
TPR repeat, putative
— OG7
TcCLB.503487.40 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507669.160 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510283.70 ⚠
glycosyl hydrolase-like protein, putative
— OG7
TcCLB.510599.30 ⚠
Component of IIS longevity pathway SMK-1, put
— OG7
TcCLB.507993.260 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506945.80 ⚠
DNA ligase I, putative
— OG7
TcCLB.511871.40 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
TcCLB.511305.10 ⚠
5'-3' exoribonuclease B, putative
— OG7
TcCLB.509967.30 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.510777.20 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.511911.21 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506779.170 ⚠
haloacid dehalogenase hydrolase, putative
— OG7
TcCLB.509965.110 ⚠
importin alpha, putative
— OG7
TcCLB.509011.40 ⚠
calreticulin, putative
— OG7
TcCLB.506773.44 ⚠
cytochrome b5, putative
— OG7
TcCLB.507047.160 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506753.110 ⚠
cytochrome b5-like protein, putative
— OG7
TcCLB.504431.109 ⚠
cytochrome b5, putative
— OG7
TcCLB.503653.60 ⚠
cytochrome b-domain protein, putative
— OG7
TcCLB.508215.9 ⚠
protein kinase C substrate protein, heavy cha
— OG7
TcCLB.509153.120 ⚠
acyl-CoA dehydrogenase, putative
— OG7
TcCLB.508465.110 ⚠
acyl-CoA dehydrogenase, putative
— OG7
TcCLB.504867.20 ⚠
ABC transporter, putative
— OG7
TcCLB.506743.80 ⚠
SMP-30/Gluconolaconase/LRE-like region, putat
— OG7
TcCLB.506773.80 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510603.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511627.120 ⚠
aldo/keto reductase, putative
— OG7
TcCLB.509103.4 ⚠
protein kinase, putative
— OG7
TcCLB.511353.4 ⚠
choline/carnitine O-acyltransferase, putative
— OG7
TcCLB.507211.10 ⚠
choline/carnitine O-acyltransferase, putative
— OG7
TcCLB.511303.40 ⚠
carnitine O-acetyltransferase, putative
— OG7
TcCLB.504137.10 ⚠
isoleucyl-tRNA synthetase, putative
— OG7
TcCLB.508723.100 ⚠
rab-like GTPase activating protein, putative
— OG7
TcCLB.508723.80 ⚠
disgorgin, putative
— OG7
TcCLB.506467.40 ⚠
serine/threonine protein kinase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.