TcCLB.506945.80

DNA ligase I, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_100906 OG7: OG7_0002598 146 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 146 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.506107.20 ⚠
dihydrouridine synthase (Dus), putative
— Both
TcCLB.510053.70 ⚠
hypothetical protein, conserved
— Both
TcCLB.506265.180 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504203.29 ⚠
tRNA-dihydrouridine synthase 2, putative
— OG7
TcCLB.506691.80
Ubiquitin-like domain containing protein, put
— Both
TcCLB.510747.10 ⚠
TFIIF-stimulated CTD phosphatase, putative
— OG7
TcCLB.509167.120
S-adenosylmethionine decarboxylase proenzyme,
— Both
TcCLB.505965.50
phosphonopyruvate decarboxylase, putative
— Both
TcCLB.399033.19 ⚠
kinetoplast polyadenylation/uridylation facto
— Both
TcCLB.509123.30 ⚠
kinetoplast polyadenylation/uridylation facto
— Both
TcCLB.511743.30
hypothetical protein, conserved
— Both
TcCLB.510533.120 ⚠
translation initiation factor IF-2, putative
— Both
TcCLB.510617.19 ⚠
hypothetical protein, conserved
— Both
TcCLB.508387.10 ⚠
hypothetical protein, conserved
— Both
TcCLB.509767.100
hypothetical protein, conserved
— Both
TcCLB.503513.10
casein kinase II, alpha chain, putative
— OG6
TcCLB.506863.10
alanyl-tRNA synthetase, putative
— Both
TcCLB.509595.50 ⚠
DIS3-like exonuclease, putative
— Both
TcCLB.509967.80 ⚠
Programmed cell death protein 2, C-terminal p
— Both
TcCLB.509769.134 ⚠
Beta-lactamase superfamily domain containing
— Both
TcCLB.510533.20 ⚠
Beta-lactamase superfamily domain containing
— Both
TcCLB.429257.10
Gar1/Naf1 RNA binding region, putative
— Both
TcCLB.508181.140 ⚠
inorganic pyrophosphatase, putative
— Both
TcCLB.503613.60 ⚠
acidocalcisomal pyrophosphatase, putative
— Both
TcCLB.508241.120 ⚠
rrp44p homologue, putative
— OG7
TcCLB.506287.30 ⚠
cytochrome b5-like Heme/Steroid binding domai
— OG7
TcCLB.506773.44 ⚠
cytochrome b5, putative
— OG7
TcCLB.507047.160 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506753.110 ⚠
cytochrome b5-like protein, putative
— OG7
TcCLB.504431.109 ⚠
cytochrome b5, putative
— OG7
TcCLB.503653.60 ⚠
cytochrome b-domain protein, putative
— OG7
TcCLB.505943.20
oxidoreductase, putative
— OG7
TcCLB.503407.10
hypothetical protein, conserved
— OG7
TcCLB.505945.20 ⚠
ribonuclease mar1, putative
— OG7
TcCLB.509103.20 ⚠
tubulin-tyrosine ligase, putative
— OG7
TcCLB.505945.30 ⚠
ribonuclease mar1, putative
— OG7
TcCLB.506775.30 ⚠
tubulin-tyrosine ligase-like protein, putativ
— OG7
TcCLB.506743.210 ⚠
tubulin tyrosine ligase, putative
— OG7
TcCLB.506941.80 ⚠
tubulin-tyrosine ligase-like protein, putativ
— OG7
TcCLB.511737.10 ⚠
small glutamine-rich tetratricopeptide repeat
— OG7
TcCLB.509381.10 ⚠
mitochondrial import receptor subunit, putati
— OG7
TcCLB.506513.50 ⚠
calcium/calmodulin-dependent protein kinase,
— OG7
TcCLB.506885.320 ⚠
TPR repeat/Tetratricopeptide repeat, putative
— OG7
TcCLB.509127.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507677.140 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
TcCLB.509967.30 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.509103.4 ⚠
protein kinase, putative
— OG7
TcCLB.511307.6 ⚠
NOL1/NOP2/sun family, putative
— OG7
TcCLB.503865.40 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
TcCLB.508463.20 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.