TcCLB.503513.10

casein kinase II, alpha chain, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_128066 OG7: OG7_0000396 46 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 46 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.505983.30
general transcription factor IIB
— OG6
TcCLB.510743.10 ⚠
ubiquitin-activating enzyme E1, putative
— OG6
TcCLB.509125.20 ⚠
ATP-dependent Clp protease subunit, heat shoc
— OG6
TcCLB.506635.40
Regulator of chromosome condensation (RCC1) r
— OG6
TcCLB.509805.80
hypothetical protein, conserved
— OG6
TcCLB.504427.250 ⚠
ubiquitin-activating enzyme E1, putative
— OG6
TcCLB.506107.20
dihydrouridine synthase (Dus), putative
— OG6
TcCLB.511747.30
C2H2 type zinc-finger (2 copies), putative
— OG6
TcCLB.510257.80
cytosolic nonspecific dipeptidase, putative
— OG6
TcCLB.508995.20
Tubulin/FtsZ family, putative
— OG6
TcCLB.508385.60
Vta1 like, putative
— OG6
TcCLB.507091.50 ⚠
aspartate carbamoyltransferase, putative
— OG6
TcCLB.508807.10 ⚠
atp-dependent chaperone, ATP-dependent Clp pr
— OG6
TcCLB.510741.229 ⚠
ubiquitin-activating enzyme E1, putative
— OG6
TcCLB.510879.40
Carboxypeptidase-like protein
— OG6
TcCLB.507993.369
13 kDa deflagellation-inducible protein, puta
— OG6
TcCLB.508209.110
hypothetical protein, conserved
— OG6
TcCLB.511911.150 ⚠
nucleotide-binding protein, putative
— OG6
TcCLB.507389.70
peptidase, putative, metallo-peptidase, Clan
— OG6
TcCLB.509965.290
p22 protein precursor, putative
— OG6
TcCLB.511051.59
Thiamin pyrophosphokinase, vitamin B1 binding
— OG6
TcCLB.510749.4 ⚠
ubiquitin-protein ligase, putative
— OG6
TcCLB.510737.100
Peroxin 19
— OG6
TcCLB.506945.80
DNA ligase I, putative
— OG6
TcCLB.503757.40
Casein kinase II subunit beta, putative
— OG6
TcCLB.511191.10
tyrosyl-DNA Phosphodiesterase (Tdp1), putativ
— OG6
TcCLB.511107.41 ⚠
ATP-dependent Clp protease subunit heat shock
— OG6
TcCLB.509167.150
homoserine kinase
— OG6
TcCLB.506025.10 ⚠
hypothetical protein, conserved
— OG6
TcCLB.510747.170 ⚠
hypothetical protein, conserved
— OG6
TcCLB.509769.134 ⚠
Beta-lactamase superfamily domain containing
— OG6
TcCLB.506375.70
Fungal tRNA ligase phosphodiesterase domain c
— OG6
TcCLB.508995.30
tubulin-tyrosine ligase, putative
— OG6
TcCLB.504625.60
hydrogenase, putative
— OG6
TcCLB.504055.60
hypothetical protein, conserved
— OG6
TcCLB.510761.60
casein kinase II, putative
— OG6
TcCLB.508583.10
Methyltransferase domain/Methyltransferase in
— OG6
TcCLB.503579.100 ⚠
nucleotide-binding protein, putative
— OG6
TcCLB.506367.20
XRN 5'-3' exonuclease N-terminus, putative
— OG6
TcCLB.510533.20 ⚠
Beta-lactamase superfamily domain containing
— OG6
TcCLB.510351.70
hypothetical protein, conserved
— OG6
TcCLB.508375.30 ⚠
aspartate carbamoyltransferase, putative
— OG6
TcCLB.511801.20
D123, putative
— OG6
TcCLB.506691.80
Ubiquitin-like domain containing protein, put
— OG6
TcCLB.509967.80
Programmed cell death protein 2, C-terminal p
— OG6
TcCLB.504077.40
translation elongation factor EF-2, putative
— OG6
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.