TcCLB.508807.10

atp-dependent chaperone, ATP-dependent Clp protease subunit, heat shock protein 104 (HSP104), putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_100223 OG7: OG7_0002479 160 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 160 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.504077.40 ⚠
translation elongation factor EF-2, putative
— Both
TcCLB.509267.50 ⚠
U5 small nuclear ribonucleoprotein component,
— Both
TcCLB.510531.30 ⚠
Galactose oxidase, central domain containing
— OG6
TcCLB.511745.10 ⚠
heat shock 70 kDa protein, mitochondrial prec
— Both
TcCLB.506941.280 ⚠
heat shock 70 kDa protein, mitochondrial prec
— Both
TcCLB.508169.9 ⚠
elongation factor 2, putative (fragment)
— OG7
TcCLB.510963.90 ⚠
elongation factor 2, putative
— OG7
TcCLB.508169.20 ⚠
elongation factor 2, putative
— OG7
TcCLB.511737.10 ⚠
small glutamine-rich tetratricopeptide repeat
— OG7
TcCLB.506025.10 ⚠
hypothetical protein, conserved
— OG6
TcCLB.503579.100 ⚠
nucleotide-binding protein, putative
— Both
TcCLB.511911.150 ⚠
nucleotide-binding protein, putative
— Both
TcCLB.504625.60 ⚠
hydrogenase, putative
— Both
TcCLB.504625.80 ⚠
hypothetical protein, conserved
— Both
TcCLB.503513.10 ⚠
casein kinase II, alpha chain, putative
— OG6
TcCLB.509769.134 ⚠
Beta-lactamase superfamily domain containing
— Both
TcCLB.510533.20 ⚠
Beta-lactamase superfamily domain containing
— Both
TcCLB.511707.39 ⚠
Importin subunit beta-4, putative
— OG7
TcCLB.510719.300 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
TcCLB.507669.160 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506885.416 ⚠
regulator of chromosome condensation (RCC1),
— OG7
TcCLB.510615.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504867.20 ⚠
ABC transporter, putative
— OG7
TcCLB.506941.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504203.29 ⚠
tRNA-dihydrouridine synthase 2, putative
— OG7
TcCLB.509537.80 ⚠
TPR repeat, putative
— OG7
TcCLB.503479.49 ⚠
U6 snRNA-associated Sm-like protein LSm7p
— OG7
TcCLB.504147.190 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510105.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510053.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506265.180 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508213.9 ⚠
regulator of chromosome condensation, putativ
— OG7
TcCLB.503489.10 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
TcCLB.509757.30 ⚠
stress-inducible protein STI1-like, putative
— OG7
TcCLB.509381.10 ⚠
mitochondrial import receptor subunit, putati
— OG7
TcCLB.506893.25 ⚠
U6 snRNA-associated Sm-like protein LSm6p
— OG7
TcCLB.510761.70 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.510091.70 ⚠
U6 snRNA-associated Sm-like protein LSm8, put
— OG7
TcCLB.508439.30 ⚠
regulator of chromosome condensation 1-like p
— OG7
TcCLB.506773.180 ⚠
regulator of chromatin condensation, putative
— OG7
TcCLB.508323.120 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508277.360 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.506885.320 ⚠
TPR repeat/Tetratricopeptide repeat, putative
— OG7
TcCLB.510593.10 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TcCLB.503579.150 ⚠
RNA editing complex protein MP57, putative, R
— OG7
TcCLB.506933.107 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507875.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509967.170 ⚠
dynein arm light chain, putative
— OG7
TcCLB.511145.43 ⚠
proteasome subunit alpha type-5, putative
— OG7
TcCLB.504075.10 ⚠
kinetoplast poly(A) polymerase 1
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.