TcCLB.504147.190

hypothetical protein, conserved
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_158309 OG7: OG7_0002947 149 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 149 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.503479.70 ⚠
hook complex protein, conserved
— OG7
TcCLB.509777.100 ⚠
ubiquitin-activating enzyme, putative
— OG7
TcCLB.506885.416 ⚠
regulator of chromosome condensation (RCC1),
— OG7
TcCLB.506893.25 ⚠
U6 snRNA-associated Sm-like protein LSm6p
— OG7
TcCLB.511585.130 ⚠
ubiquitin activating enzyme, putative
— OG7
TcCLB.509551.64 ⚠
small nuclear ribonucleoprotein Sm-F, putativ
— OG7
TcCLB.506635.40 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TcCLB.510091.70 ⚠
U6 snRNA-associated Sm-like protein LSm8, put
— OG7
TcCLB.509965.30 ⚠
small nuclear ribonucleoprotein Sm-E, putativ
— OG7
TcCLB.510105.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508213.9 ⚠
regulator of chromosome condensation, putativ
— OG7
TcCLB.508439.30 ⚠
regulator of chromosome condensation 1-like p
— OG7
TcCLB.506773.180 ⚠
regulator of chromatin condensation, putative
— OG7
TcCLB.510593.10 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TcCLB.508211.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510761.70 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.508277.360 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.506745.4 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcCLB.506743.220 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506367.20 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
TcCLB.510601.30 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
TcCLB.511801.20 ⚠
D123, putative
— OG7
TcCLB.505843.10 ⚠
glutamate dehydrogenase, putative
— OG7
TcCLB.509445.39 ⚠
glutamate dehydrogenase, putative
— OG7
TcCLB.507993.369 ⚠
13 kDa deflagellation-inducible protein, puta
— OG7
TcCLB.508583.10 ⚠
Methyltransferase domain/Methyltransferase in
— OG7
TcCLB.506457.130 ⚠
Domain of unknown function (DUF4042), putativ
— OG7
TcCLB.506859.70 ⚠
guide RNA associated protein, GAP2, putative
— OG7
TcCLB.510609.130 ⚠
hypothetical protein, conserved
— OG7
TcCLB.464807.20 ⚠
PA26 p53-induced protein (sestrin), putative
— OG7
TcCLB.510101.210 ⚠
PUB domain containing protein, putative
— OG7
TcCLB.504055.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510431.220 ⚠
ribosome assembly protein RRB1, putative
— OG7
TcCLB.508585.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507711.320 ⚠
DNA mismatch repair protein MSH2, putative
— OG7
TcCLB.508465.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504159.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508539.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503579.100 ⚠
nucleotide-binding protein, putative
— OG7
TcCLB.511729.9 ⚠
calmodulin, putative (fragment)
— OG7
TcCLB.507809.110 ⚠
WD domain, G-beta repeat, putative
— OG7
TcCLB.503959.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511751.180 ⚠
pseudouridine synthase A-like protein, putati
— OG7
TcCLB.503579.110 ⚠
pseudouridylate synthase I, putative
— OG7
TcCLB.509153.110 ⚠
hypothetical protein
— OG7
TcCLB.510615.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508323.120 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509965.290 ⚠
p22 protein precursor, putative
— OG7
TcCLB.508995.20 ⚠
Tubulin/FtsZ family, putative
— OG7
TcCLB.506289.70 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.