TcCLB.506289.70

hypothetical protein, conserved
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_215192 OG7: OG7_0052326 78 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 78 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.506755.279
hypothetical protein, conserved
— OG7
TcCLB.511751.180 ⚠
pseudouridine synthase A-like protein, putati
— OG7
TcCLB.507929.20
co-chaperone GrpE, putative
— OG7
TcCLB.504147.190 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510769.70 ⚠
hypothetical protein
— OG7
TcCLB.507711.320
DNA mismatch repair protein MSH2, putative
— OG7
TcCLB.508585.10
hypothetical protein, conserved
— OG7
TcCLB.509965.350 ⚠
ubiquitin-protein ligase, putative
— OG7
TcCLB.503959.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510431.220 ⚠
ribosome assembly protein RRB1, putative
— OG7
TcCLB.508465.60
hypothetical protein, conserved
— OG7
TcCLB.509153.110
hypothetical protein
— OG7
TcCLB.507809.110
WD domain, G-beta repeat, putative
— OG7
TcCLB.510101.210
PUB domain containing protein, putative
— OG7
TcCLB.464807.20
PA26 p53-induced protein (sestrin), putative
— OG7
TcCLB.510609.130
hypothetical protein, conserved
— OG7
TcCLB.506859.70
guide RNA associated protein, GAP2, putative
— OG7
TcCLB.506457.130
Domain of unknown function (DUF4042), putativ
— OG7
TcCLB.509965.30 ⚠
small nuclear ribonucleoprotein Sm-E, putativ
— OG7
TcCLB.510091.70 ⚠
U6 snRNA-associated Sm-like protein LSm8, put
— OG7
TcCLB.503479.70 ⚠
hook complex protein, conserved
— OG7
TcCLB.506375.80
hypothetical protein, conserved
— OG7
TcCLB.511429.20
cyclophilin 15, putative
— OG7
TcCLB.509597.4 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510749.4 ⚠
ubiquitin-protein ligase, putative
— OG7
TcCLB.507875.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506885.380
hypothetical protein, conserved
— OG7
TcCLB.511577.50
endo-beta-N-acetylglucosaminidase, putative
— OG7
TcCLB.511729.9 ⚠
calmodulin, putative (fragment)
— OG7
TcCLB.510741.40
hypothetical protein, conserved
— OG7
TcCLB.509551.64 ⚠
small nuclear ribonucleoprotein Sm-F, putativ
— OG7
TcCLB.511217.160 ⚠
WW domain containing protein, putative
— OG7
TcCLB.507747.220 ⚠
protein farnesyltransferase, putative
— OG7
TcCLB.510323.10
protein kinase, putative
— OG7
TcCLB.510747.170 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508539.50
hypothetical protein, conserved
— OG7
TcCLB.504159.60
hypothetical protein, conserved
— OG7
TcCLB.503579.110 ⚠
pseudouridylate synthase I, putative
— OG7
TcCLB.506945.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508787.30 ⚠
pumilio/PUF RNA binding protein 3, putative
— OG7
TcCLB.507093.90 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509835.10 ⚠
Ring finger domain containing protein, putati
— OG7
TcCLB.510243.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504087.10 ⚠
Ring finger domain containing protein, putati
— OG7
TcCLB.506563.10 ⚠
pumilio/PUF RNA binding protein 9, putative
— OG7
TcCLB.510125.10 ⚠
pumilio/PUF RNA binding protein 6, putative
— OG7
TcCLB.509759.19 ⚠
pumilio/PUF RNA binding protein 1, putative
— OG7
TcCLB.507831.110 ⚠
pumilio/PUF RNA binding protein 2, putative
— OG7
TcCLB.510073.30 ⚠
pumilio/PUF RNA binding protein 4, putative
— OG7
TcCLB.511467.16 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.