TcCLB.509759.19

pumilio/PUF RNA binding protein 1, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_134860 OG7: OG7_0001979 54 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 54 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.509823.4 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511737.9 ⚠
Translation machinery associated TMA7, putati
— OG7
TcCLB.511729.9 ⚠
calmodulin, putative (fragment)
— OG7
TcCLB.511735.79 ⚠
Translation machinery associated TMA7, putati
— OG7
TcCLB.511127.250 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508779.40 ⚠
Ring finger domain containing protein, putati
— OG7
TcCLB.508277.190 ⚠
ERAD-associated E3 ubiquitin-protein ligase H
— OG7
TcCLB.510841.10 ⚠
Kinesin-13 4b, putative (fragment)
— OG7
TcCLB.510749.4 ⚠
ubiquitin-protein ligase, putative
— OG7
TcCLB.506513.24 ⚠
Ring finger domain containing protein, putati
— OG7
TcCLB.509805.50 ⚠
AN1-like zinc finger, putative
— OG7
TcCLB.504133.45 ⚠
Temperature dependent protein affecting M2 ds
— OG7
TcCLB.506945.70 ⚠
protein mkt1, putative
— OG7
TcCLB.503971.5 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509767.220 ⚠
Ring finger domain containing protein, putati
— OG7
TcCLB.504147.240 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504147.250 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508777.40 ⚠
leucine-rich repeat protein, putative
— OG7
TcCLB.511535.20 ⚠
Rab-like 5, small G protein
— OG7
TcCLB.511577.160 ⚠
kinetoplastid kinetochore protein 18
— OG7
TcCLB.507875.170 ⚠
ribosomal P protein AGP2beta-1, putative
— OG7
TcCLB.509165.34 ⚠
ribosomal P protein AGP2beta-1, putative
— OG7
TcCLB.510609.130 ⚠
hypothetical protein, conserved
— OG7
TcCLB.464807.20 ⚠
PA26 p53-induced protein (sestrin), putative
— OG7
TcCLB.445553.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507993.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510293.30 ⚠
Eukaryotic translation initiation factor 4E t
— OG7
TcCLB.503579.110 ⚠
pseudouridylate synthase I, putative
— OG7
TcCLB.511751.70 ⚠
microtubule associated protein xmap215
— OG7
TcCLB.510431.220 ⚠
ribosome assembly protein RRB1, putative
— OG7
TcCLB.503959.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511429.20 ⚠
cyclophilin 15, putative
— OG7
TcCLB.506895.40 ⚠
Kinesin-13 1, putative
— OG7
TcCLB.504087.10 ⚠
Ring finger domain containing protein, putati
— OG7
TcCLB.510769.70 ⚠
hypothetical protein
— OG7
TcCLB.504147.190 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511751.180 ⚠
pseudouridine synthase A-like protein, putati
— OG7
TcCLB.508277.65 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506945.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509589.30 ⚠
Kinesin-13 5, putative
— OG7
TcCLB.510243.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506543.100 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504125.60 ⚠
Kinesin-13 3, putative
— OG7
TcCLB.504427.50 ⚠
5'-AMP-activated protein kinase subunit beta,
— OG7
TcCLB.509769.30 ⚠
Inositol hexakisphosphate, putative
— OG7
TcCLB.504159.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508921.30 ⚠
Kinesin-13 4, putative
— OG7
TcCLB.509835.10 ⚠
Ring finger domain containing protein, putati
— OG7
TcCLB.506289.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507093.90 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.