TcCLB.511577.160

kinetoplastid kinetochore protein 18
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_157997 OG7: OG7_0051936 55 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:
Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 55 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.506563.10 ⚠
pumilio/PUF RNA binding protein 9, putative
— OG7
TcCLB.508277.360 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— Both
TcCLB.508237.9 ⚠
protein kinase, putative
— Both
TcCLB.506777.120 ⚠
eukaryotic translation initiation factor 2-al
— Both
TcCLB.509805.60 ⚠
Ras-related protein Rab5A, putative
— OG6
TcCLB.506227.180 ⚠
ras-related protein RAB5B, putative
— OG6
TcCLB.397937.10 ⚠
pumilio/PUF RNA binding protein 1, putative
— OG7
TcCLB.507521.110 ⚠
pumilio/PUF RNA binding protein 5, putative
— OG7
TcCLB.503971.5 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508787.30 ⚠
pumilio/PUF RNA binding protein 3, putative
— OG7
TcCLB.510073.30 ⚠
pumilio/PUF RNA binding protein 4, putative
— OG7
TcCLB.509823.4 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509759.19 ⚠
pumilio/PUF RNA binding protein 1, putative
— OG7
TcCLB.504147.250 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511435.30
MORN repeat-containing protein
— Both
TcCLB.506517.100 ⚠
ATPase family associated with various cellula
— OG7
TcCLB.510755.147 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507395.14
hypothetical protein, conserved
— OG7
TcCLB.511741.30 ⚠
replication factor C, subunit 2, putative
— OG7
TcCLB.508647.40 ⚠
replication factor C, subunit 1, putative
— OG7
TcCLB.511589.160 ⚠
replication factor C, subunit 4, putative
— OG7
TcCLB.510737.110 ⚠
replication factor C, subunit 3, putative
— OG7
TcCLB.511575.120 ⚠
JAB1/Mov34/MPN/PAD-1 ubiquitin protease, puta
— OG7
TcCLB.510761.70 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.506633.80 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511435.20 ⚠
Replication Factor C Subunit 1-related protei
— OG7
TcCLB.510757.9 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcCLB.510231.10 ⚠
eukaryotic translation initiation factor 2-al
— OG7
TcCLB.507011.250
Putative death-receptor fusion protein (DUF24
— Both
TcCLB.510293.30
Eukaryotic translation initiation factor 4E t
— Both
TcCLB.510125.10 ⚠
pumilio/PUF RNA binding protein 6, putative
— Both
TcCLB.506543.100
hypothetical protein, conserved
— Both
TcCLB.507993.70
hypothetical protein, conserved
— Both
TcCLB.507831.110 ⚠
pumilio/PUF RNA binding protein 2, putative
— Both
TcCLB.511535.20
Rab-like 5, small G protein
— Both
TcCLB.507875.170 ⚠
ribosomal P protein AGP2beta-1, putative
— Both
TcCLB.509165.34 ⚠
ribosomal P protein AGP2beta-1, putative
— Both
TcCLB.510759.200 ⚠
hypothetical protein, conserved
— Both
TcCLB.506941.260
hypothetical protein, conserved
— Both
TcCLB.508995.50
hypothetical protein, conserved
— Both
TcCLB.503525.20
Cyclin 12, L-type
— Both
TcCLB.506753.90
hypothetical protein, conserved
— Both
TcCLB.504147.240 ⚠
hypothetical protein, conserved
— Both
TcCLB.503821.10 ⚠
RNA-binding protein RBP10, putative, DNA-dire
— Both
TcCLB.503651.4 ⚠
hypothetical protein, conserved (fragment)
— Both
TcCLB.506829.50
Ring finger domain/Zn-finger in ubiquitin-hyd
— Both
TcCLB.506503.120
hypothetical protein, conserved
— Both
TcCLB.511737.20
hypothetical protein, conserved
— Both
TcCLB.506635.120 ⚠
kinesin, putative
— OG6
TcCLB.504171.50
hypothetical protein, conserved
— Both
Page 1 of 2
Next →
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.