TcCLB.503821.10

RNA-binding protein RBP10, putative, DNA-directed RNA polymerase I subunit, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_101548 OG7: OG7_0007040 60 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 60 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.510029.40 ⚠
DNA-directed RNA polymerase III subunit C11,
— OG7
TcCLB.506941.260 ⚠
hypothetical protein, conserved
— Both
TcCLB.503525.20 ⚠
Cyclin 12, L-type
— Both
TcCLB.507011.250 ⚠
Putative death-receptor fusion protein (DUF24
— Both
TcCLB.503651.4 ⚠
hypothetical protein, conserved (fragment)
— Both
TcCLB.511737.20 ⚠
hypothetical protein, conserved
— Both
TcCLB.506635.120 ⚠
kinesin, putative
— OG6
TcCLB.504171.50 ⚠
hypothetical protein, conserved
— Both
TcCLB.506413.40 ⚠
hypothetical protein, conserved
— Both
TcCLB.506635.110 ⚠
kinesin-like protein, putative
— OG6
TcCLB.504153.150 ⚠
Unc104-like kinesin, putative
— OG6
TcCLB.511575.120 ⚠
JAB1/Mov34/MPN/PAD-1 ubiquitin protease, puta
— OG7
TcCLB.506633.80 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506517.100 ⚠
ATPase family associated with various cellula
— OG7
TcCLB.510283.114 ⚠
DNA-directed RNA polymerase I subunit, putati
— OG7
TcCLB.510759.200 ⚠
hypothetical protein, conserved
— Both
TcCLB.511741.30 ⚠
replication factor C, subunit 2, putative
— OG7
TcCLB.508647.40 ⚠
replication factor C, subunit 1, putative
— OG7
TcCLB.511589.160 ⚠
replication factor C, subunit 4, putative
— OG7
TcCLB.510737.110 ⚠
replication factor C, subunit 3, putative
— OG7
TcCLB.511435.20 ⚠
Replication Factor C Subunit 1-related protei
— OG7
TcCLB.510231.10 ⚠
eukaryotic translation initiation factor 2-al
— OG7
TcCLB.510755.147 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507395.14 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510757.9 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcCLB.510761.70 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.506503.110 ⚠
DNA-directed RNA polymerases I and III subuni
— OG7
TcCLB.506925.40 ⚠
RNA polymerase I second largest subunit, puta
— OG7
TcCLB.506357.100 ⚠
DNA-directed RNA polymerase I subunit RPB5z,
— OG7
TcCLB.503819.20 ⚠
DNA-directed RNA polymerase III subunit, puta
— OG7
TcCLB.403789.9 ⚠
DNA-directed RNA polymerase I largest subunit
— Both
TcCLB.506777.120 ⚠
eukaryotic translation initiation factor 2-al
— Both
TcCLB.507509.30 ⚠
RNA polymerase-like protein, putative
— Both
TcCLB.511435.30 ⚠
MORN repeat-containing protein
— Both
TcCLB.511801.44 ⚠
DNA-dependent RNA polymerases, putative
— Both
TcCLB.506779.60 ⚠
DNA-direcetd RNA polymerase II, subunit 9, pu
— Both
TcCLB.506357.90 ⚠
DNA-directed RNA polymerase II/III subunit, p
— Both
TcCLB.506753.90 ⚠
hypothetical protein, conserved
— Both
TcCLB.506933.80 ⚠
RNA polymerase B subunit RPB8, putative
— Both
TcCLB.508277.360 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— Both
TcCLB.506503.120 ⚠
hypothetical protein, conserved
— Both
TcCLB.511423.104 ⚠
DNA-directed RNA polymerase 2, RPB12 subunit,
— Both
TcCLB.503953.50 ⚠
Beta-lactamase superfamily domain containing
— Both
TcCLB.508995.50 ⚠
hypothetical protein, conserved
— Both
TcCLB.511577.160 ⚠
kinetoplastid kinetochore protein 18
— Both
TcCLB.508237.9 ⚠
protein kinase, putative
— Both
TcCLB.443683.9 ⚠
DNA-directed rna polymerase I largest subunit
— Both
TcCLB.507485.34 ⚠
DNA-directed RNA polymerase III subunit, puta
— Both
TcCLB.506949.10 ⚠
DNA-directed rna polymerase I largest subunit
— Both
TcCLB.509011.20 ⚠
RNA polymerase IIA largest subunit, putative
— Both
Page 1 of 2
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.