TcCLB.510029.40

DNA-directed RNA polymerase III subunit C11, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_101491 OG7: OG7_0002891 53 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 53 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.507817.9 ⚠
histone H3, putative
— OG7
TcCLB.509453.40 ⚠
DNA-directed RNA polymerase I subunit RPB10,
— OG7
TcCLB.510525.110 ⚠
histone H2A, putative
— OG7
TcCLB.507673.65 ⚠
DNA-directed RNA polymerase subunit, putative
— OG7
TcCLB.510143.90 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511801.44 ⚠
DNA-dependent RNA polymerases, putative
— OG7
TcCLB.510525.90 ⚠
histone H2A, putative
— OG7
TcCLB.508973.80 ⚠
RAVE protein 1 C terminal, putative
— OG7
TcCLB.506863.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509297.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503579.30 ⚠
DNA polymerase sigma-like protein, putative
— OG7
TcCLB.506401.100 ⚠
DNA polymerase sigma, putative
— OG7
TcCLB.506357.90 ⚠
DNA-directed RNA polymerase II/III subunit, p
— OG7
TcCLB.506357.100 ⚠
DNA-directed RNA polymerase I subunit RPB5z,
— OG7
TcCLB.508839.89 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
TcCLB.505931.40 ⚠
histone H3, putative
— OG7
TcCLB.506503.150 ⚠
histone H3 variant V
— OG7
TcCLB.505931.50 ⚠
histone H3, putative
— OG7
TcCLB.507817.18 ⚠
histone H3, putative
— OG7
TcCLB.503453.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503819.20 ⚠
DNA-directed RNA polymerase III subunit, puta
— OG7
TcCLB.507509.30 ⚠
RNA polymerase-like protein, putative
— OG7
TcCLB.506625.200 ⚠
exosome complex exonuclease, putative, riboso
— OG7
TcCLB.508209.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511423.104 ⚠
DNA-directed RNA polymerase 2, RPB12 subunit,
— OG7
TcCLB.504133.45 ⚠
Temperature dependent protein affecting M2 ds
— OG7
TcCLB.506945.70 ⚠
protein mkt1, putative
— OG7
TcCLB.510525.80 ⚠
histone H2A, putative
— OG7
TcCLB.506563.20 ⚠
exosome-associated protein 1, putative
— OG7
TcCLB.510771.9 ⚠
Thioredoxin-like/Protein of unknown function
— OG7
TcCLB.510773.9 ⚠
Thioredoxin-like/Protein of unknown function
— OG7
TcCLB.504883.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509011.20 ⚠
RNA polymerase IIA largest subunit, putative
— OG7
TcCLB.506949.10 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
TcCLB.509951.49 ⚠
DNA-directed RNA polymerase II subunit 2, put
— OG7
TcCLB.507979.4 ⚠
histone H2A variant Z (fragment)
— OG7
TcCLB.508321.11 ⚠
histone H2A, putative (fragment)
— OG7
TcCLB.507485.15 ⚠
DNA-directed RNA polymerase subunit, putative
— OG7
TcCLB.506503.110 ⚠
DNA-directed RNA polymerases I and III subuni
— OG7
TcCLB.506513.200 ⚠
histone H2A variant Z (fragment)
— OG7
TcCLB.507143.70 ⚠
Galactose oxidase, central domain/Kelch motif
— OG7
TcCLB.510525.100 ⚠
histone H2A, putative
— OG7
TcCLB.403789.9 ⚠
DNA-directed RNA polymerase I largest subunit
— OG7
TcCLB.508321.21 ⚠
histone H2A, putative
— OG7
TcCLB.443683.9 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
TcCLB.507485.34 ⚠
DNA-directed RNA polymerase III subunit, puta
— OG7
TcCLB.503821.10 ⚠
RNA-binding protein RBP10, putative, DNA-dire
— OG7
TcCLB.506925.40 ⚠
RNA polymerase I second largest subunit, puta
— OG7
TcCLB.507467.94 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506933.80 ⚠
RNA polymerase B subunit RPB8, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.