TcCLB.506563.20

exosome-associated protein 1, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_146086 OG7: OG7_0043575 39 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 39 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.506625.200
exosome complex exonuclease, putative, riboso
— Both
TcCLB.508179.60
protein kinase, putative
— OG6
TcCLB.511211.170 ⚠
heat shock protein 70 (hsp70), putative
— OG6
TcCLB.506863.50 ⚠
ribosomal RNA processing protein 45, putative
— Both
TcCLB.507671.30
25 kDa translation elongation factor 1-beta
— Both
TcCLB.509543.50 ⚠
DNAK protein, putative
— OG6
TcCLB.509455.50 ⚠
hypothetical protein, conserved
— Both
TcCLB.508813.15 ⚠
heat shock protein 70, putative (fragment)
— OG6
TcCLB.508973.80
RAVE protein 1 C terminal, putative
— Both
TcCLB.506401.100 ⚠
DNA polymerase sigma, putative
— Both
TcCLB.509767.180
exosome component CSL4, putative
— Both
TcCLB.506779.60 ⚠
DNA-direcetd RNA polymerase II, subunit 9, pu
— OG7
TcCLB.506945.70 ⚠
protein mkt1, putative
— OG7
TcCLB.510029.40 ⚠
DNA-directed RNA polymerase III subunit C11,
— OG7
TcCLB.509297.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503579.30 ⚠
DNA polymerase sigma-like protein, putative
— OG7
TcCLB.509951.49 ⚠
DNA-directed RNA polymerase II subunit 2, put
— OG7
TcCLB.503579.40 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503653.30 ⚠
ribosomal RNA processing protein 41B, putativ
— OG7
TcCLB.511417.40 ⚠
DNA-directed RNA polymerase III, putative
— OG7
TcCLB.510105.20 ⚠
Ribosomal RNA processing protein 41A
— Both
TcCLB.507143.70
Galactose oxidase, central domain/Kelch motif
— Both
TcCLB.503453.70
hypothetical protein, conserved
— Both
TcCLB.510771.9 ⚠
Thioredoxin-like/Protein of unknown function
— Both
TcCLB.504133.45 ⚠
Temperature dependent protein affecting M2 ds
— Both
TcCLB.510283.114 ⚠
DNA-directed RNA polymerase I subunit, putati
— Both
TcCLB.506863.70
hypothetical protein, conserved
— Both
TcCLB.510773.9 ⚠
Thioredoxin-like/Protein of unknown function
— Both
TcCLB.509965.180
RNA-binding protein, putative
— OG6
TcCLB.508209.70
hypothetical protein, conserved
— Both
TcCLB.511211.220 ⚠
heat shock protein 70, putative
— OG6
TcCLB.510167.29
ribosomal RNA processing protein 4, putative,
— Both
TcCLB.418069.10 ⚠
heat shock protein 70 (hsp70), putative (frag
— OG6
TcCLB.506135.9 ⚠
heat shock 70 kDa protein, putative (fragment
— OG6
TcCLB.506925.40 ⚠
RNA polymerase I second largest subunit, puta
— Both
TcCLB.503813.10
hypothetical protein, conserved
— Both
TcCLB.507841.34 ⚠
exosome-associated protein 4, putative
— Both
TcCLB.511211.160 ⚠
heat shock protein 70 (hsp70), putative
— OG6
TcCLB.507089.80 ⚠
exosome-associated protein 2, putative
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.