TcCLB.506863.50

ribosomal RNA processing protein 45, putative, exosome complex exonuclease, putative, 3' exoribonuclease, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_100420 OG7: OG7_0002825 73 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 73 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.510167.29 ⚠
ribosomal RNA processing protein 4, putative,
— +4 more Both
TcCLB.506625.200 ⚠
exosome complex exonuclease, putative, riboso
— +2 more Both
TcCLB.504057.110 ⚠
exosome complex exonuclease, putative, riboso
— Both
TcCLB.503653.30 ⚠
ribosomal RNA processing protein 41B, putativ
— +2 more Both
TcCLB.510105.20 ⚠
Ribosomal RNA processing protein 41A
— +2 more Both
TcCLB.507841.34 ⚠
exosome-associated protein 4, putative
— OG7
TcCLB.511211.160 ⚠
heat shock protein 70 (hsp70), putative
— OG6
TcCLB.511211.220 ⚠
heat shock protein 70, putative
— OG6
TcCLB.506135.9 ⚠
heat shock 70 kDa protein, putative (fragment
— OG6
TcCLB.418069.10 ⚠
heat shock protein 70 (hsp70), putative (frag
— OG6
TcCLB.507089.80 ⚠
exosome-associated protein 2, putative
— Both
TcCLB.506779.50 ⚠
proteasome beta 3 subunit, putative
— Both
TcCLB.503613.20 ⚠
proteasome alpha 7 subunit, putative
— Both
TcCLB.507671.30 ⚠
25 kDa translation elongation factor 1-beta
— Both
TcCLB.508469.59 ⚠
helicase, putative
— OG6
TcCLB.510515.139 ⚠
T-complex protein 1, gamma subunit, putative
— Both
TcCLB.510517.10 ⚠
chaperonin/T-complex protein 1 gamma subunit,
— Both
TcCLB.506775.180 ⚠
hypothetical protein, conserved
— Both
TcCLB.509455.50 ⚠
hypothetical protein, conserved
— Both
TcCLB.506691.14 ⚠
ATP-dependent DEAD/H RNA helicase, putative (
— Both
TcCLB.507083.80 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511145.43 ⚠
proteasome subunit alpha type-5, putative
— OG7
TcCLB.508357.90 ⚠
T-complex protein 1, beta subunit, putative
— OG7
TcCLB.506167.40 ⚠
proteasome subunit alpha type-1, putative
— OG7
TcCLB.510105.9 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcCLB.509583.10 ⚠
chaperonin TCP20, putative
— OG7
TcCLB.506503.110 ⚠
DNA-directed RNA polymerases I and III subuni
— OG7
TcCLB.504213.120 ⚠
proteasome alpha 3 subunit, putative
— OG7
TcCLB.511867.50 ⚠
proteasome alpha 7 subunit, putative
— OG7
TcCLB.509767.180 ⚠
exosome component CSL4, putative
— Both
TcCLB.507809.30 ⚠
ribose-phosphate pyrophosphokinase, putative
— OG7
TcCLB.511417.40 ⚠
DNA-directed RNA polymerase III, putative
— OG7
TcCLB.503579.40 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509951.49 ⚠
DNA-directed RNA polymerase II subunit 2, put
— OG7
TcCLB.508813.15 ⚠
heat shock protein 70, putative (fragment)
— OG6
TcCLB.509543.50 ⚠
DNAK protein, putative
— OG6
TcCLB.511211.170 ⚠
heat shock protein 70 (hsp70), putative
— OG6
TcCLB.511531.40 ⚠
chaperonin alpha subunit, putative
— Both
TcCLB.510879.30 ⚠
hypothetical protein, conserved
— Both
TcCLB.506607.19 ⚠
phosphoribosylpyrophosphate synthetase, putat
— Both
TcCLB.506795.90 ⚠
'Cold-shock' DNA-binding domain containing pr
— Both
TcCLB.507923.40 ⚠
hypothetical protein, conserved
— Both
TcCLB.506755.20 ⚠
paraflagellar rod component, putative
— Both
TcCLB.468941.9 ⚠
ATP-dependent DEAD/H RNA helicase, putative (
— Both
TcCLB.508369.50 ⚠
acetyl-CoA carboxylase (fragment)
— Both
TcCLB.506135.110 ⚠
mitochondrial RNA binding complex 1 subunit,
— Both
TcCLB.504867.40 ⚠
acetyltransferase, putative
— Both
TcCLB.507811.20 ⚠
delta-adaptin, putative, adaptor complex prot
— Both
TcCLB.510557.50 ⚠
mucin TcMUCII, putative
— OG6
TcCLB.506563.20 ⚠
exosome-associated protein 1, putative
— Both
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.