TcCLB.507923.40

hypothetical protein, conserved
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_157001 OG7: OG7_0051147 68 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 68 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.510879.30
hypothetical protein, conserved
— Both
TcCLB.506503.110
DNA-directed RNA polymerases I and III subuni
— Both
TcCLB.506607.19 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcCLB.508717.30 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcCLB.503777.19 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcCLB.507875.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511217.160 ⚠
WW domain containing protein, putative
— OG7
TcCLB.509965.350 ⚠
ubiquitin-protein ligase, putative
— OG7
TcCLB.510599.14 ⚠
acetyl-CoA carboxylase (fragment)
— Both
TcCLB.504179.40
hypothetical protein, conserved
— Both
TcCLB.510229.10
hypothetical protein, conserved
— Both
TcCLB.508369.50 ⚠
acetyl-CoA carboxylase (fragment)
— Both
TcCLB.510557.50 ⚠
mucin TcMUCII, putative
— OG6
TcCLB.507093.10
hypothetical protein, conserved
— Both
TcCLB.506357.130
hypothetical protein, conserved
— Both
TcCLB.503531.49 ⚠
structural maintenance of chromosome 3, putat
— Both
TcCLB.507813.10 ⚠
structural maintenance of chromosome 3 protei
— Both
TcCLB.504427.140
hypothetical protein, conserved
— Both
TcCLB.509769.70 ⚠
DNA polymerase theta (helicase domain only),
— OG7
TcCLB.507603.40 ⚠
proteasome beta-1 subunit, putative
— OG7
TcCLB.507083.80 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507011.60 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
TcCLB.508779.90 ⚠
structural maintenance of chromosome protein
— OG7
TcCLB.508357.40 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TcCLB.510749.40 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
TcCLB.509073.30 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.510243.50 ⚠
UMP/CMP kinase, putative
— OG7
TcCLB.510431.250 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcCLB.504051.20 ⚠
ATP-dependent DNA DEAD/DEAH box helicase, put
— OG7
TcCLB.504159.80 ⚠
histone deacetylase, putative
— OG7
TcCLB.510753.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510755.19 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504033.200 ⚠
hypothetical protein
— OG7
TcCLB.511589.80 ⚠
tubulin binding cofactor c, putative
— OG7
TcCLB.505945.80
AKAP7 2'5' RNA ligase-like domain containing
— Both
TcCLB.511583.30
hypothetical protein, conserved
— Both
TcCLB.503595.10
hypothetical protein, conserved
— Both
TcCLB.510101.110
hypothetical protein, conserved
— Both
TcCLB.506287.80
FYVE zinc finger, putative
— OG6
TcCLB.505941.49 ⚠
hypothetical protein, conserved
— Both
TcCLB.506775.60
hypothetical protein, conserved
— Both
TcCLB.505943.10 ⚠
hypothetical protein, conserved
— Both
TcCLB.503885.40
hypothetical protein, conserved
— Both
TcCLB.511395.70
hypothetical protein, conserved
— Both
TcCLB.507089.80 ⚠
exosome-associated protein 2, putative
— Both
TcCLB.506265.120
hypothetical protein, conserved
— Both
TcCLB.507639.40 ⚠
proteasome subunit beta type-5, putative
— Both
TcCLB.511127.20 ⚠
flagellar pocket cytoskeletal protein bilbo1
— Both
TcCLB.506925.110
hypothetical protein, conserved
— Both
TcCLB.507811.20
delta-adaptin, putative, adaptor complex prot
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.