TcCLB.508369.50

acetyl-CoA carboxylase (fragment)
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_101052 OG7: OG7_0001434 181 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 181 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.506607.19 ⚠
phosphoribosylpyrophosphate synthetase, putat
— +5 more Both
TcCLB.503777.19 ⚠
phosphoribosylpyrophosphate synthetase, putat
— +5 more Both
TcCLB.507809.30 ⚠
ribose-phosphate pyrophosphokinase, putative
— +5 more Both
TcCLB.510431.250 ⚠
phosphoribosylpyrophosphate synthetase, putat
— +6 more Both
TcCLB.508717.30 ⚠
phosphoribosylpyrophosphate synthetase, putat
— +6 more Both
TcCLB.509769.70 ⚠
DNA polymerase theta (helicase domain only),
— OG7
TcCLB.504051.20 ⚠
ATP-dependent DNA DEAD/DEAH box helicase, put
— OG7
TcCLB.511313.40 ⚠
ATP-dependent RNA helicase, putative
— Both
TcCLB.506179.59 ⚠
ATP-dependent RNA helicase, putative (fragmen
— Both
TcCLB.511315.9 ⚠
ATP-dependent RNA helicase, putative
— Both
TcCLB.509625.10 ⚠
ATP-dependent RNA helicase, putative (fragmen
— Both
TcCLB.403789.9 ⚠
DNA-directed RNA polymerase I largest subunit
— Both
TcCLB.443683.9 ⚠
DNA-directed rna polymerase I largest subunit
— Both
TcCLB.506949.10 ⚠
DNA-directed rna polymerase I largest subunit
— Both
TcCLB.401473.9 ⚠
DNA-directed RNA polymerase I largest subunit
— Both
TcCLB.508839.89 ⚠
DNA-directed rna polymerase I largest subunit
— Both
TcCLB.504119.4 ⚠
DNA-directed RNA polymerase III subunit C1, p
— Both
TcCLB.509011.20 ⚠
RNA polymerase IIA largest subunit, putative
— Both
TcCLB.511217.160 ⚠
WW domain containing protein, putative
— OG7
TcCLB.510105.210 ⚠
mitochondrial ATP-dependent zinc metallopepti
— +2 more OG7
TcCLB.506167.40 ⚠
proteasome subunit alpha type-1, putative
— OG7
TcCLB.510105.9 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcCLB.504213.120 ⚠
proteasome alpha 3 subunit, putative
— OG7
TcCLB.507639.40 ⚠
proteasome subunit beta type-5, putative
— OG7
TcCLB.511867.50 ⚠
proteasome alpha 7 subunit, putative
— OG7
TcCLB.507739.20 ⚠
mitochondrial ATP-dependent zinc metallopepti
— +2 more OG7
TcCLB.507213.10 ⚠
hypothetical protein, conserved
— +2 more OG7
TcCLB.508357.90 ⚠
T-complex protein 1, beta subunit, putative
— OG7
TcCLB.509583.10 ⚠
chaperonin TCP20, putative
— OG7
TcCLB.503613.20 ⚠
proteasome alpha 7 subunit, putative
— Both
TcCLB.507603.40 ⚠
proteasome beta-1 subunit, putative
— Both
TcCLB.510855.40 ⚠
proteasome regulatory non-ATPase subunit, put
— Both
TcCLB.511365.10 ⚠
hypothetical protein, conserved
— Both
TcCLB.506691.14 ⚠
ATP-dependent DEAD/H RNA helicase, putative (
— Both
TcCLB.504427.140 ⚠
hypothetical protein, conserved
— Both
TcCLB.507813.10 ⚠
structural maintenance of chromosome 3 protei
— Both
TcCLB.503531.49 ⚠
structural maintenance of chromosome 3, putat
— Both
TcCLB.506945.240 ⚠
ATP synthase, epsilon chain, putative
— Both
TcCLB.508921.20 ⚠
hypothetical protein, conserved
— Both
TcCLB.510841.20 ⚠
hypothetical protein, conserved
— Both
TcCLB.505123.20 ⚠
hypothetical protein, conserved
— Both
TcCLB.506357.130 ⚠
hypothetical protein, conserved
— Both
TcCLB.509951.49 ⚠
DNA-directed RNA polymerase II subunit 2, put
— OG7
TcCLB.507875.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507395.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509965.350 ⚠
ubiquitin-protein ligase, putative
— OG7
TcCLB.504883.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511417.40 ⚠
DNA-directed RNA polymerase III, putative
— OG7
TcCLB.510771.9 ⚠
Thioredoxin-like/Protein of unknown function
— Both
TcCLB.506779.50 ⚠
proteasome beta 3 subunit, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.