TcCLB.506691.14

ATP-dependent DEAD/H RNA helicase, putative (fragment)
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_105684 OG7: OG7_0002665 134 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 134 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.507797.9 ⚠
nuclear transcription factor, putative
— OG7
TcCLB.511867.50 ⚠
proteasome alpha 7 subunit, putative
— +1 more Both
TcCLB.503653.20 ⚠
hypothetical protein, conserved
— Both
TcCLB.510557.50 ⚠
mucin TcMUCII, putative
— OG6
TcCLB.508369.50 ⚠
acetyl-CoA carboxylase (fragment)
— Both
TcCLB.510599.14 ⚠
acetyl-CoA carboxylase (fragment)
— Both
TcCLB.503613.20 ⚠
proteasome alpha 7 subunit, putative
— +1 more Both
TcCLB.506779.50 ⚠
proteasome beta 3 subunit, putative
— Both
TcCLB.504019.9 ⚠
Importin-beta N-terminal domain/HEAT-like rep
— OG7
TcCLB.511529.9 ⚠
Importin-beta N-terminal domain/HEAT-like rep
— OG7
TcCLB.511707.39 ⚠
Importin subunit beta-4, putative
— OG7
TcCLB.511423.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504077.40 ⚠
translation elongation factor EF-2, putative
— OG7
TcCLB.510743.10 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
TcCLB.509267.50 ⚠
U5 small nuclear ribonucleoprotein component,
— OG7
TcCLB.504427.250 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
TcCLB.508169.20 ⚠
elongation factor 2, putative
— OG7
TcCLB.510741.229 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
TcCLB.510963.90 ⚠
elongation factor 2, putative
— OG7
TcCLB.508169.9 ⚠
elongation factor 2, putative (fragment)
— OG7
TcCLB.509885.60 ⚠
methyltransferase, putative
— OG7
TcCLB.509583.10 ⚠
chaperonin TCP20, putative
— OG7
TcCLB.508357.90 ⚠
T-complex protein 1, beta subunit, putative
— OG7
TcCLB.507809.30 ⚠
ribose-phosphate pyrophosphokinase, putative
— OG7
TcCLB.507639.40 ⚠
proteasome subunit beta type-5, putative
— OG7
TcCLB.504213.120 ⚠
proteasome alpha 3 subunit, putative
— OG7
TcCLB.506167.40 ⚠
proteasome subunit alpha type-1, putative
— OG7
TcCLB.511145.43 ⚠
proteasome subunit alpha type-5, putative
— OG7
TcCLB.508469.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.505807.180 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— OG7
TcCLB.511871.40 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
TcCLB.508465.110 ⚠
acyl-CoA dehydrogenase, putative
— OG7
TcCLB.503489.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510719.300 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
TcCLB.510879.40 ⚠
Carboxypeptidase-like protein
— OG7
TcCLB.508557.29 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
TcCLB.509967.30 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.510349.30 ⚠
phosphatidylinositol-4-phosphate 5-kinase, pu
— OG7
TcCLB.507841.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511305.20 ⚠
Centrosomal protein of 164 kDa, putative
— OG7
TcCLB.430539.10 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
TcCLB.511353.40 ⚠
eukaryotic translation initiation factor 4E (
— OG7
TcCLB.511435.20 ⚠
Replication Factor C Subunit 1-related protei
— OG7
TcCLB.510181.140 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508469.4 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcCLB.510751.40 ⚠
Importin 1 (fragment)
— OG7
TcCLB.509153.110 ⚠
hypothetical protein
— OG7
TcCLB.509597.4 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507875.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503489.10 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.