TcCLB.507639.40

proteasome subunit beta type-5, putative

Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_100897 OG7: OG7_0001933 54 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Interactions 54 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TcCLB.506167.40 ⚠ proteasome subunit alpha type-1, putative	—	OG6 Tb11.v5.0196 ↔ Tb927.10.6080 OG6 Tb927.10.6030 ↔ Tb927.10.6080 OG6 LdBPK_361670.1 ↔ LdBPK_361730.1 OG7 LdBPK_120030.1 ↔ LdBPK_270190.1 +44 more	Both
TcCLB.416883.18 ⚠ proteasome alpha 2 subunit, putative	—	OG6 Tb927.10.290 ↔ Tb927.10.6080 OG6 LdBPK_212070.1 ↔ LdBPK_361730.1 OG7 LdBPK_120030.1 ↔ LdBPK_270190.1 OG7 LdBPK_120030.1 ↔ LdBPK_212070.1 +43 more	Both
TcCLB.506779.50 ⚠ proteasome beta 3 subunit, putative	—	OG6 Tb927.10.6080 ↔ Tb927.11.7270 OG6 LdBPK_280110.1 ↔ LdBPK_361730.1 OG7 LdBPK_120030.1 ↔ LdBPK_280110.1 OG7 LdBPK_280110.1 ↔ LdBPK_353880.1 +5 more	Both
TcCLB.504213.120 ⚠ proteasome alpha 3 subunit, putative	—	OG6 Tb927.10.6080 ↔ Tb927.7.4420 OG6 LdBPK_140310.1 ↔ LdBPK_361730.1 OG7 LdBPK_120030.1 ↔ LdBPK_270190.1 OG7 LdBPK_120030.1 ↔ LdBPK_212070.1 +43 more	Both
TcCLB.511867.50 ⚠ proteasome alpha 7 subunit, putative	—	OG6 Tb927.10.6080 ↔ Tb927.3.780 OG6 LdBPK_270190.1 ↔ LdBPK_361730.1 OG7 LdBPK_120030.1 ↔ LdBPK_270190.1 OG7 LdBPK_120030.1 ↔ LdBPK_212070.1 +43 more	Both
TcCLB.507521.50 ⚠ proteasome beta 6 subunit, putative, 20S prot	—	OG6 Tb927.10.6080 ↔ Tb927.7.4790 OG6 LdBPK_060140.1 ↔ LdBPK_361730.1 OG7 TCSYLVIO_002482 ↔ TCSYLVIO_006999 OG7 LdBPK_060140.1 ↔ LdBPK_120030.1 +4 more	Both
TcCLB.506885.350 ⚠ proteasome alpha 1 subunit, putative	—	OG6 Tb927.10.6080 ↔ Tb927.9.9670 OG6 LdBPK_354910.1 ↔ LdBPK_361730.1 OG7 LdBPK_120030.1 ↔ LdBPK_270190.1 OG7 LdBPK_120030.1 ↔ LdBPK_212070.1 +43 more	Both
TcCLB.507603.40 ⚠ proteasome beta-1 subunit, putative	—	OG6 LdBPK_120030.1 ↔ LdBPK_361730.1 OG6 Tb927.10.6080 ↔ Tb927.6.1260 OG7 LdBPK_120030.1 ↔ LdBPK_353880.1 OG7 LdBPK_120030.1 ↔ LdBPK_361730.1 +3 more	Both
TcCLB.511145.43 ⚠ proteasome subunit alpha type-5, putative	—	OG6 Tb927.10.230 ↔ Tb927.10.6080 OG6 LdBPK_212200.1 ↔ LdBPK_361730.1 OG7 LdBPK_120030.1 ↔ LdBPK_270190.1 OG7 LdBPK_120030.1 ↔ LdBPK_212070.1 +43 more	Both
TcCLB.510287.30 ⚠ proteasome subunit beta type-2, putative	—	OG6 LdBPK_360340.1 ↔ LdBPK_361730.1 OG6 Tb927.10.4710 ↔ Tb927.10.6080 OG7 LdBPK_120030.1 ↔ LdBPK_360340.1 OG7 LdBPK_353880.1 ↔ LdBPK_360340.1 +4 more	Both
TcCLB.503613.20 ⚠ proteasome alpha 7 subunit, putative	—	OG6 LdBPK_110240.1 ↔ LdBPK_361730.1 OG6 Tb927.10.6080 ↔ Tb927.11.7020 OG7 LdBPK_120030.1 ↔ LdBPK_270190.1 OG7 LdBPK_120030.1 ↔ LdBPK_212070.1 +43 more	Both
TcCLB.510313.20 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_004479 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004479 ↔ TCSYLVIO_006999	OG7
TcCLB.468941.9 ⚠ ATP-dependent DEAD/H RNA helicase, putative (	—	OG7 TCSYLVIO_004479 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004479 ↔ TCSYLVIO_006999	OG7
TcCLB.510599.14 ⚠ acetyl-CoA carboxylase (fragment)	—	OG7 TCSYLVIO_002772 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_002772 ↔ TCSYLVIO_006999	OG7
TcCLB.506775.180 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_001704 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_001704 ↔ TCSYLVIO_006999	OG7
TcCLB.508369.50 ⚠ acetyl-CoA carboxylase (fragment)	—	OG7 TCSYLVIO_002772 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_002772 ↔ TCSYLVIO_006999	OG7
TcCLB.506691.14 ⚠ ATP-dependent DEAD/H RNA helicase, putative (	—	OG7 TCSYLVIO_004479 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004479 ↔ TCSYLVIO_006999	OG7
TcCLB.510105.9 ⚠ ATP-dependent DEAD/H RNA helicase, putative	—	OG7 TCSYLVIO_004479 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004479 ↔ TCSYLVIO_006999	OG7
TcCLB.504119.10 ⚠ eukaryotic translation initiation factor 5, p	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_006999	OG7
TcCLB.504867.40 ⚠ acetyltransferase, putative	—	OG7 TCSYLVIO_004519 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004519 ↔ TCSYLVIO_006999	OG7
TcCLB.507809.30 ⚠ ribose-phosphate pyrophosphokinase, putative	—	OG7 TCSYLVIO_006999 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_005774 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_006999	OG7
TcCLB.430737.20 ⚠ hypothetical protein, conserved (fragment)	—	OG7 TCSYLVIO_006999 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005774 ↔ TCSYLVIO_010606	OG7
TcCLB.507083.80 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_004939 ↔ TCSYLVIO_006469	OG7
TcCLB.503777.19 ⚠ phosphoribosylpyrophosphate synthetase, putat	—	OG7 TCSYLVIO_006999 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_005774 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_006999	OG7
TcCLB.506503.110 ⚠ DNA-directed RNA polymerases I and III subuni	—	OG7 TCSYLVIO_004939 ↔ TCSYLVIO_010718	OG7
TcCLB.506607.19 ⚠ phosphoribosylpyrophosphate synthetase, putat	—	OG7 TCSYLVIO_006999 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_005774 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_006999	OG7
TcCLB.506795.90 ⚠ 'Cold-shock' DNA-binding domain containing pr	—	OG7 TCSYLVIO_006999 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005774 ↔ TCSYLVIO_010606	OG7
TcCLB.510431.250 ⚠ phosphoribosylpyrophosphate synthetase, putat	—	OG7 TCSYLVIO_006999 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_005774 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_006999	OG7
TcCLB.508717.30 ⚠ phosphoribosylpyrophosphate synthetase, putat	—	OG7 TCSYLVIO_006999 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_005774 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_006999	OG7
TcCLB.504057.110 ⚠ exosome complex exonuclease, putative, riboso	—	OG7 TCSYLVIO_003804 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_003804 ↔ TCSYLVIO_006999	OG7
TcCLB.509069.20 ⚠ ATP binding protein-like protein, putative	—	OG7 TCSYLVIO_000453 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_000453 ↔ TCSYLVIO_006999	OG7
TcCLB.511621.180 ⚠ Phosducin, putative	—	OG7 TCSYLVIO_000453 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_000453 ↔ TCSYLVIO_006999	OG7
TcCLB.507923.40 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_003184 ↔ TCSYLVIO_004939 OG7 TCSYLVIO_003184 ↔ TCSYLVIO_004939	Both
TcCLB.511127.20 ⚠ flagellar pocket cytoskeletal protein bilbo1	—	OG6 TCSYLVIO_004939 ↔ TCSYLVIO_006469 OG7 TCSYLVIO_004939 ↔ TCSYLVIO_006469	Both
TcCLB.503885.40 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001310 ↔ TCSYLVIO_004939 OG7 TCSYLVIO_001310 ↔ TCSYLVIO_004939	Both
TcCLB.511583.30 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_003433 ↔ TCSYLVIO_004939 OG7 TCSYLVIO_003433 ↔ TCSYLVIO_004939	Both
TcCLB.506265.120 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_003934 ↔ TCSYLVIO_004939 OG7 TCSYLVIO_003934 ↔ TCSYLVIO_004939	Both
TcCLB.509073.119 ⚠ proteasome regulatory non-ATP-ase subunit 7,	—	OG6 Tb927.10.6080 ↔ Tb927.11.16030 OG7 Tb927.10.6080 ↔ Tb927.11.16030	Both
TcCLB.507089.80 ⚠ exosome-associated protein 2, putative	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_004939 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004939 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_006999	Both
TcCLB.506863.50 ⚠ ribosomal RNA processing protein 45, putative	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_004939 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004939 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_006999	Both
TcCLB.510167.29 ⚠ ribosomal RNA processing protein 4, putative,	—	OG6 TCSYLVIO_004939 ↔ TCSYLVIO_010369 OG7 TCSYLVIO_004939 ↔ TCSYLVIO_010369	Both
TcCLB.506755.20 ⚠ paraflagellar rod component, putative	—	OG6 TCSYLVIO_004939 ↔ TCSYLVIO_006797 OG7 TCSYLVIO_004939 ↔ TCSYLVIO_006797	Both
TcCLB.507811.20 ⚠ delta-adaptin, putative, adaptor complex prot	—	OG6 TCSYLVIO_004939 ↔ TCSYLVIO_010530 OG7 TCSYLVIO_004939 ↔ TCSYLVIO_010530	Both
TcCLB.506925.110 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_004939 ↔ TCSYLVIO_007412 OG7 TCSYLVIO_004939 ↔ TCSYLVIO_007412	Both
TcCLB.511531.40 ⚠ chaperonin alpha subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_006999 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_006999 +2 more	OG7
TcCLB.511395.70 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_004939 ↔ TCSYLVIO_009798 OG7 TCSYLVIO_004939 ↔ TCSYLVIO_009798	Both
TcCLB.506135.110 ⚠ mitochondrial RNA binding complex 1 subunit,	—	OG6 TCSYLVIO_002300 ↔ TCSYLVIO_004939 OG7 TCSYLVIO_002300 ↔ TCSYLVIO_004939	Both
TcCLB.510879.30 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_003828 ↔ TCSYLVIO_004939 OG7 TCSYLVIO_003828 ↔ TCSYLVIO_004939	Both
TcCLB.506251.40 ⚠ hypothetical protein	—	OG7 TCSYLVIO_004631 ↔ TCSYLVIO_006999	OG7
TcCLB.510517.10 ⚠ chaperonin/T-complex protein 1 gamma subunit,	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_006999 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_006999 +2 more	OG7

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