TcCLB.504119.10

eukaryotic translation initiation factor 5, putative

Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_101859 OG7: OG7_0007078 57 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 57 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TcCLB.510105.9 ⚠ ATP-dependent DEAD/H RNA helicase, putative	—	OG7 TCSYLVIO_004479 ↔ TCSYLVIO_004556	OG7
TcCLB.508717.30 ⚠ phosphoribosylpyrophosphate synthetase, putat	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_004731 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_004731	Both
TcCLB.511303.60 eukaryotic translation initiation factor 3 su	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_008900 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008900	Both
TcCLB.511531.40 ⚠ chaperonin alpha subunit, putative	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008271	Both
TcCLB.416883.18 ⚠ proteasome alpha 2 subunit, putative	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556	Both
TcCLB.507603.40 ⚠ proteasome beta-1 subunit, putative	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_006999 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_006999	Both
TcCLB.508469.59 helicase, putative	—	OG6 TCSYLVIO_001373 ↔ TCSYLVIO_004556	OG6
TcCLB.506943.160 eukaryotic translation initiation factor 3 su	—	OG6 TCSYLVIO_003333 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_003333 ↔ TCSYLVIO_004556	Both
TcCLB.510557.50 ⚠ mucin TcMUCII, putative	—	OG6 TCSYLVIO_002772 ↔ TCSYLVIO_004556	OG6
TcCLB.508369.50 ⚠ acetyl-CoA carboxylase (fragment)	—	OG6 TCSYLVIO_002772 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_002772 ↔ TCSYLVIO_004556	Both
TcCLB.510599.14 ⚠ acetyl-CoA carboxylase (fragment)	—	OG6 TCSYLVIO_002772 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_002772 ↔ TCSYLVIO_004556	Both
TcCLB.503613.20 ⚠ proteasome alpha 7 subunit, putative	—	OG6 TCSYLVIO_001707 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556	Both
TcCLB.506779.50 proteasome beta 3 subunit, putative	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_004556	Both
TcCLB.509583.10 ⚠ chaperonin TCP20, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008271	OG7
TcCLB.508357.90 ⚠ T-complex protein 1, beta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008271	OG7
TcCLB.506963.10 60S ribosomal protein L10a, putative	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_006190 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_006190	Both
TcCLB.507809.30 ⚠ ribose-phosphate pyrophosphokinase, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_004731	OG7
TcCLB.506211.70 ⚠ RNA-binding protein, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_006059	OG7
TcCLB.511867.50 ⚠ proteasome alpha 7 subunit, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556	OG7
TcCLB.507639.40 ⚠ proteasome subunit beta type-5, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_006999	OG7
TcCLB.508973.50 ⚠ ATP-dependent RNA helicase DBP2B, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	OG7
TcCLB.504213.120 ⚠ proteasome alpha 3 subunit, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556	OG7
TcCLB.506167.40 ⚠ proteasome subunit alpha type-1, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556	OG7
TcCLB.503595.19 ⚠ ATP-dependent DEAD/H RNA helicase, putative (	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	OG7
TcCLB.506213.120 ⚠ ATP-dependent RNA helicase HEL67	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	OG7
TcCLB.511801.60 ⚠ DEAD-box ATP-dependent RNA helicase, mitochon	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	OG7
TcCLB.511145.43 ⚠ proteasome subunit alpha type-5, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556	OG7
TcCLB.511571.10 ⚠ ATP-dependent DEAD/H RNA helicase, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	OG7
TcCLB.507811.30 ⚠ ATP-dependent DEAD/H RNA helicase, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	OG7
TcCLB.510717.30 ⚠ 2-oxoglutarate dehydrogenase E1 component, pu	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_005469 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005469	Both
TcCLB.503971.50 hypothetical protein, conserved	—	OG6 Tb927.10.2770 ↔ Tb927.11.11010 OG7 Tb927.10.2770 ↔ Tb927.11.11010	Both
TcCLB.468941.9 ⚠ ATP-dependent DEAD/H RNA helicase, putative (	—	OG6 TCSYLVIO_004479 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004479 ↔ TCSYLVIO_004556	Both
TcCLB.510313.20 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_004479 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004479 ↔ TCSYLVIO_004556	Both
TcCLB.506691.14 ⚠ ATP-dependent DEAD/H RNA helicase, putative (	—	OG6 TCSYLVIO_004479 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004479 ↔ TCSYLVIO_004556	Both
TcCLB.509069.20 ⚠ ATP binding protein-like protein, putative	—	OG6 TCSYLVIO_000453 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_000453 ↔ TCSYLVIO_004556	Both
TcCLB.511621.180 ⚠ Phosducin, putative	—	OG6 TCSYLVIO_000453 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_000453 ↔ TCSYLVIO_004556	Both
TcCLB.504057.110 exosome complex exonuclease, putative, riboso	—	OG6 TCSYLVIO_003804 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_003804 ↔ TCSYLVIO_004556	Both
TcCLB.507089.80 ⚠ exosome-associated protein 2, putative	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004556	Both
TcCLB.506863.50 ⚠ ribosomal RNA processing protein 45, putative	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004556	Both
TcCLB.506775.180 hypothetical protein, conserved	—	OG6 TCSYLVIO_001704 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_001704 ↔ TCSYLVIO_004556	Both
TcCLB.504867.40 acetyltransferase, putative	—	OG6 TCSYLVIO_004519 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004519 ↔ TCSYLVIO_004556	Both
TcCLB.510517.10 ⚠ chaperonin/T-complex protein 1 gamma subunit,	—	OG6 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008271	Both
TcCLB.510515.139 ⚠ T-complex protein 1, gamma subunit, putative	—	OG6 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008271	Both
TcCLB.510877.150 eukaryotic translation initiation factor 3 su	—	OG6 TCSYLVIO_003837 ↔ TCSYLVIO_004556	OG6
TcCLB.506211.60 ⚠ RNA-binding protein, putative	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_006059 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_006059	Both
TcCLB.503715.10 splicing factor TSR1, putative	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_009720 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009720	Both
TcCLB.506795.90 ⚠ 'Cold-shock' DNA-binding domain containing pr	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_010606	Both
TcCLB.506607.19 ⚠ phosphoribosylpyrophosphate synthetase, putat	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_004731	Both
TcCLB.504163.110 n-alpha-acetyltransferase 15, NatA auxiliary	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_010020 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_010020	Both
TcCLB.510741.180 ⚠ ATP-dependent RNA helicase, putative	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_005835 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	Both

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