TcCLB.503715.10

splicing factor TSR1, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_139901 OG7: OG7_0042904 53 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 53 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.503893.60 ⚠
UBA/TS-N domain containing protein, putative
— OG7
TcCLB.506211.60 ⚠
RNA-binding protein, putative
— Both
TcCLB.506529.50 ⚠
arginine N-methyltransferase, putative
— Both
TcCLB.504119.10
eukaryotic translation initiation factor 5, p
— Both
TcCLB.504163.110
n-alpha-acetyltransferase 15, NatA auxiliary
— Both
TcCLB.506943.160
eukaryotic translation initiation factor 3 su
— Both
TcCLB.510741.180 ⚠
ATP-dependent RNA helicase, putative
— Both
TcCLB.510321.20 ⚠
NOL1/NOP2/sun family, putative
— OG7
TcCLB.506699.3 ⚠
NOL1/NOP2/sun family, putative
— OG7
TcCLB.511307.6 ⚠
NOL1/NOP2/sun family, putative
— OG7
TcCLB.509153.100 ⚠
protein arginine n-methyltransferase 7
— OG7
TcCLB.506947.80 ⚠
arginine N-methyltransferase, type I
— OG7
TcCLB.509967.160 ⚠
epsilon tubulin, putative
— OG7
TcCLB.504867.20
ABC transporter, putative
— OG7
TcCLB.506963.10
60S ribosomal protein L10a, putative
— Both
TcCLB.506677.10 ⚠
ubiquitin-like protein, putative
— OG7
TcCLB.504867.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503969.10 ⚠
tubulin delta chain
— OG7
TcCLB.511871.40 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
TcCLB.511867.190 ⚠
tubulin gamma chain
— OG7
TcCLB.508973.50 ⚠
ATP-dependent RNA helicase DBP2B, putative
— OG7
TcCLB.503595.19 ⚠
ATP-dependent DEAD/H RNA helicase, putative (
— OG7
TcCLB.506213.120 ⚠
ATP-dependent RNA helicase HEL67
— OG7
TcCLB.511801.60 ⚠
DEAD-box ATP-dependent RNA helicase, mitochon
— OG7
TcCLB.511571.10 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcCLB.507811.30 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcCLB.506211.70 ⚠
RNA-binding protein, putative
— OG7
TcCLB.511001.240 ⚠
proteasome activator protein pa26, putative
— Both
TcCLB.506493.30
hypothetical protein, conserved
— Both
TcCLB.510311.140 ⚠
arginine N-methyltransferase, putative
— Both
TcCLB.511303.60
eukaryotic translation initiation factor 3 su
— Both
TcCLB.506625.70
RNA-binding protein, putative
— OG6
TcCLB.508277.230 ⚠
nucleolar RNA binding protein, putative
— Both
TcCLB.509805.40 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— Both
TcCLB.506211.250 ⚠
fibrillarin, putative
— Both
TcCLB.510105.50 ⚠
fibrillarin, putative
— Both
TcCLB.506737.70
ubiquitin-like protein, putative
— OG6
TcCLB.506563.40 ⚠
beta tubulin, putative
— Both
TcCLB.505807.180 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— Both
TcCLB.506737.20
CMGC/MAPK protein kinase, putative
— Both
TcCLB.510877.150
eukaryotic translation initiation factor 3 su
— OG6
TcCLB.510743.10 ⚠
ubiquitin-activating enzyme E1, putative
— Both
TcCLB.503841.10 ⚠
proteasome activator protein pa26, putative
— Both
TcCLB.504427.250 ⚠
ubiquitin-activating enzyme E1, putative
— Both
TcCLB.506659.30
glutathione synthetase, putative
— Both
TcCLB.510603.30 ⚠
hypothetical protein, conserved
— Both
TcCLB.510741.229 ⚠
ubiquitin-activating enzyme E1, putative
— Both
TcCLB.509801.10
hypothetical protein, conserved
— Both
TcCLB.506743.170 ⚠
Met-10+ like-protein, putative
— Both
TcCLB.510717.30 ⚠
2-oxoglutarate dehydrogenase E1 component, pu
— Both
Page 1 of 2
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.