TcCLB.504867.110

hypothetical protein, conserved
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_104709 OG7: OG7_0003743 97 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 97 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.511303.30 ⚠
methyltransferase domain containing protein,
— OG7
TcCLB.511127.250 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509767.220 ⚠
Ring finger domain containing protein, putati
— OG7
TcCLB.511467.16 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507093.90 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509835.10 ⚠
Ring finger domain containing protein, putati
— OG7
TcCLB.510243.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504087.10 ⚠
Ring finger domain containing protein, putati
— OG7
TcCLB.511585.40 ⚠
DNA-damage inducible protein DDI1-like protei
— OG7
TcCLB.510181.9 ⚠
inositol-3-phosphate synthase, putative (frag
— OG7
TcCLB.503639.10 ⚠
inositol-3-phosphate synthase, putative
— OG7
TcCLB.506677.10 ⚠
ubiquitin-like protein, putative
— OG7
TcCLB.503893.60 ⚠
UBA/TS-N domain containing protein, putative
— OG7
TcCLB.508779.40 ⚠
Ring finger domain containing protein, putati
— OG7
TcCLB.417091.10 ⚠
RNA pseudouridylate synthase, putative
— OG7
TcCLB.508271.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507735.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503551.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511871.40 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
TcCLB.509167.170 ⚠
tRNA (Guanine-1)-methyltransferase, putative
— OG7
TcCLB.510741.229 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
TcCLB.511313.20 ⚠
Phosphorylated CTD interacting factor 1 WW do
— OG7
TcCLB.509595.50 ⚠
DIS3-like exonuclease, putative
— OG7
TcCLB.506127.20 ⚠
mRNA export factor MEX67
— OG7
TcCLB.510777.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506895.40 ⚠
Kinesin-13 1, putative
— OG7
TcCLB.506737.20 ⚠
CMGC/MAPK protein kinase, putative
— OG7
TcCLB.510841.10 ⚠
Kinesin-13 4b, putative (fragment)
— OG7
TcCLB.511419.10 ⚠
hypothetical protein
— OG7
TcCLB.506265.209 ⚠
Shwachman-Bodian-Diamond syndrome (SBDS) prot
— OG7
TcCLB.505123.28 ⚠
Kinesin-13 4, putative
— OG7
TcCLB.508921.30 ⚠
Kinesin-13 4, putative
— OG7
TcCLB.504125.60 ⚠
Kinesin-13 3, putative
— OG7
TcCLB.509589.30 ⚠
Kinesin-13 5, putative
— OG7
TcCLB.511747.30 ⚠
C2H2 type zinc-finger (2 copies), putative
— OG7
TcCLB.504055.10 ⚠
Shwachman-Bodian-Diamond syndrome (SBDS) prot
— OG7
TcCLB.507257.70 ⚠
protein farnesyltransferase alpha subunit, pu
— OG7
TcCLB.505807.180 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— OG7
TcCLB.509167.200 ⚠
Protein of unknown function (DUF544), putativ
— OG7
TcCLB.506227.230 ⚠
N-alpha-acetyltransferase 10, NatA catalytic
— OG7
TcCLB.506825.130 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506659.30 ⚠
glutathione synthetase, putative
— OG7
TcCLB.511867.190 ⚠
tubulin gamma chain
— OG7
TcCLB.503969.10 ⚠
tubulin delta chain
— OG7
TcCLB.506563.40 ⚠
beta tubulin, putative
— OG7
TcCLB.509967.160 ⚠
epsilon tubulin, putative
— OG7
TcCLB.503715.10 ⚠
splicing factor TSR1, putative
— OG7
TcCLB.506513.24 ⚠
Ring finger domain containing protein, putati
— OG7
TcCLB.508277.190 ⚠
ERAD-associated E3 ubiquitin-protein ligase H
— OG7
TcCLB.511691.30 ⚠
ubiquitin activating enzyme, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.