TcCLB.505807.180

2-hydroxy-3-oxopropionate reductase, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_101839 OG7: OG7_0002731 224 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:
Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 224 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.503893.60 ⚠
UBA/TS-N domain containing protein, putative
— Both
TcCLB.506677.10 ⚠
ubiquitin-like protein, putative
— OG7
TcCLB.508387.40 ⚠
Mitochondrial large ribosomal subunit mL63, p
— OG7
TcCLB.509537.80 ⚠
TPR repeat, putative
— OG7
TcCLB.509965.380 ⚠
dTDP-glucose 4,6-dehydratase, putative
— OG7
TcCLB.507993.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.420989.10 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.507669.160 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510777.29 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
TcCLB.511305.10 ⚠
5'-3' exoribonuclease B, putative
— OG7
TcCLB.510719.150 ⚠
Mitochondrial small ribosomal subunit mS47, p
— OG7
TcCLB.506779.170 ⚠
haloacid dehalogenase hydrolase, putative
— OG7
TcCLB.504153.190 ⚠
Mitochondrial small ribosomal subunit mS52, p
— OG7
TcCLB.506367.140 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506869.40 ⚠
Mitochondrial large ribosomal subunit mL75, p
— OG7
TcCLB.504867.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511627.120 ⚠
aldo/keto reductase, putative
— OG7
TcCLB.509099.80 ⚠
Mitochondrial small ribosomal subunit mS49, p
— OG7
TcCLB.503575.54 ⚠
Mitochondrial small ribosomal subunit mS59, p
— OG7
TcCLB.508169.9 ⚠
elongation factor 2, putative (fragment)
— OG7
TcCLB.510963.90 ⚠
elongation factor 2, putative
— OG7
TcCLB.508169.20 ⚠
elongation factor 2, putative
— OG7
TcCLB.509267.50 ⚠
U5 small nuclear ribonucleoprotein component,
— OG7
TcCLB.511603.130 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507011.90 ⚠
Mitochondrial small ribosomal subunit mS26, p
— OG7
TcCLB.509979.230 ⚠
Mitochondrial small ribosomal subunit mS34, p
— OG7
TcCLB.504239.90 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511739.20 ⚠
Mitochondrial large ribosomal subunit mL72, p
— OG7
TcCLB.506625.90 ⚠
Mitochondrial large ribosomal subunit mL94, p
— OG7
TcCLB.510603.30 ⚠
hypothetical protein, conserved
— Both
TcCLB.507641.80 ⚠
5'-3' exoribonuclease D, putative
— Both
TcCLB.504077.40 ⚠
translation elongation factor EF-2, putative
— Both
TcCLB.506659.30 ⚠
glutathione synthetase, putative
— Both
TcCLB.511693.70 ⚠
hypothetical protein, conserved
— Both
TcCLB.509767.90 ⚠
alanine racemase, putative
— Both
TcCLB.511693.90 ⚠
electron-transfer-flavoprotein, alpha polypep
— Both
TcCLB.506737.20 ⚠
CMGC/MAPK protein kinase, putative
— Both
TcCLB.506931.10 ⚠
haloacid dehalogenase-like hydrolase, putativ
— Both
TcCLB.503841.70 ⚠
aspartate aminotransferase, putative
— Both
TcCLB.509955.10 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— Both
TcCLB.509953.9 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— Both
TcCLB.511115.40 ⚠
transcription elongation factor s-II, putativ
— Both
TcCLB.511423.110 ⚠
hypothetical protein, conserved
— Both
TcCLB.506227.120 ⚠
hypothetical protein, conserved
— OG7
TcCLB.505123.28 ⚠
Kinesin-13 4, putative
— OG7
TcCLB.510841.10 ⚠
Kinesin-13 4b, putative (fragment)
— OG7
TcCLB.506227.110 ⚠
Mitochondrial large ribosomal subunit mL52, p
— OG7
TcCLB.508921.30 ⚠
Kinesin-13 4, putative
— OG7
TcCLB.511553.80 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506743.30 ⚠
50S ribosomal protein L17, putative
— OG7
Page 1 of 5
Next →
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.