TcCLB.510777.29

Eukaryotic translation initiation factor 4E-4 (fragment)
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_106272 OG7: OG7_0002303 206 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 206 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.510105.9 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcCLB.503813.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509205.110 ⚠
elongation factor G2-like protein, putative
— OG7
TcCLB.506635.60 ⚠
pyroglutamyl-peptidase I, putative
— OG7
TcCLB.510257.130 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
TcCLB.506747.20 ⚠
dihydroorotase, putative
— OG7
TcCLB.510719.60 ⚠
Biotin--acetyl-CoA-carboxylase ligase, putati
— OG7
TcCLB.507603.30 ⚠
PITH domain-containing protein
— OG7
TcCLB.506795.44 ⚠
Bifunctional NAD(P)H-hydrate repair enzyme
— OG7
TcCLB.511911.130 ⚠
phosphoglucomutase
— OG7
TcCLB.510525.10 ⚠
calcium/calmodulin-dependent protein kinase,
— OG7
TcCLB.506359.60 ⚠
UTP-glucose-1-phosphate uridylyltransferase 2
— OG7
TcCLB.506677.39 ⚠
Elongation factor G1, mitochondrial, putative
— OG7
TcCLB.503991.39 ⚠
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldola
— OG7
TcCLB.503805.10 ⚠
Mitochondrial Editosome-like Complex TUTase
— OG7
TcCLB.503697.120 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503713.30 ⚠
6-phosphogluconolactonase, putative
— OG7
TcCLB.506659.39 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.509007.70 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.509537.80 ⚠
TPR repeat, putative
— OG7
TcCLB.420989.10 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.506221.30 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.507669.160 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503841.70 ⚠
aspartate aminotransferase, putative
— OG7
TcCLB.407477.30 ⚠
diphthine synthase, putative
— OG7
TcCLB.503959.78 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510611.79 ⚠
Present in the outer mitochondrial membrane p
— OG7
TcCLB.506779.170 ⚠
haloacid dehalogenase hydrolase, putative
— OG7
TcCLB.507817.80 ⚠
5'-3' exoribonuclease A, putative (fragment)
— OG7
TcCLB.511305.10 ⚠
5'-3' exoribonuclease B, putative
— OG7
TcCLB.506351.9 ⚠
5'-3' exoribonuclease A, putative (fragment)
— OG7
TcCLB.507641.80 ⚠
5'-3' exoribonuclease D, putative
— OG7
TcCLB.503613.60 ⚠
acidocalcisomal pyrophosphatase, putative
— OG7
TcCLB.505807.180 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— OG7
TcCLB.511871.40 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
TcCLB.508181.140 ⚠
inorganic pyrophosphatase, putative
— OG7
TcCLB.504147.30 ⚠
Protein of unknown function (DUF2870), putati
— OG7
TcCLB.511215.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508085.10 ⚠
GMP synthase, putative
— OG7
TcCLB.510323.20 ⚠
Flagellum attachment zone protein 19, putativ
— OG7
TcCLB.507841.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510859.50 ⚠
Domain of unknown function (DUF3437), putativ
— OG7
TcCLB.510861.14 ⚠
Domain of unknown function (DUF3437), putativ
— OG7
TcCLB.506249.20 ⚠
protein transport protein Sec23A, putative
— OG7
TcCLB.506949.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510311.90 ⚠
quinone oxidoreductase, putative
— OG7
TcCLB.509965.330 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511801.50 ⚠
tRNA threonylcarbamoyl adenosine modification
— OG7
TcCLB.507797.9 ⚠
nuclear transcription factor, putative
— OG7
TcCLB.509757.30 ⚠
stress-inducible protein STI1-like, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.