TcCLB.511305.10

5'-3' exoribonuclease B, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_156818 OG7: OG7_0003221 188 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 188 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.504029.101 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511353.40 ⚠
eukaryotic translation initiation factor 4E (
— OG7
TcCLB.510595.20 ⚠
KH domain/Domain of unknown function (DUF1771
— OG7
TcCLB.511575.60 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— OG7
TcCLB.511801.50 ⚠
tRNA threonylcarbamoyl adenosine modification
— OG7
TcCLB.511737.10 ⚠
small glutamine-rich tetratricopeptide repeat
— OG7
TcCLB.508373.20 ⚠
dihydroorotase, putative
— OG7
TcCLB.511871.40 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
TcCLB.509953.9 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TcCLB.506591.20 ⚠
U-box domain protein, putative
— OG7
TcCLB.507993.150 ⚠
Activator of Hsp90 ATPase, N-terminal/Activat
— OG7
TcCLB.506525.80 ⚠
N-myristoyl transferase, putative
— OG7
TcCLB.508955.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503685.30 ⚠
carnitine/choline acetyltransferase, putative
— OG7
TcCLB.511001.60 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
TcCLB.511625.40 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.506493.50 ⚠
CAMK/CAMKL pseudokinase, putative
— OG7
TcCLB.507941.100 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504147.30 ⚠
Protein of unknown function (DUF2870), putati
— OG7
TcCLB.509453.4 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509551.70 ⚠
Co-chaperone protein P23
— OG7
TcCLB.506779.170 ⚠
haloacid dehalogenase hydrolase, putative
— OG7
TcCLB.511577.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511215.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508085.10 ⚠
GMP synthase, putative
— OG7
TcCLB.506533.34 ⚠
phosphatidylinositol kinase related protein,
— OG7
TcCLB.511435.49 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
TcCLB.506223.120 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
TcCLB.410961.10 ⚠
phosphatidylinositol kinase related protein,
— OG7
TcCLB.506949.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507603.200 ⚠
proteasome regulatory ATPase subunit 3, putat
— OG7
TcCLB.509247.30 ⚠
CCR4-NOT transcription complex subunit 1
— OG7
TcCLB.507213.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509965.350 ⚠
ubiquitin-protein ligase, putative
— OG7
TcCLB.511143.12 ⚠
Microtubule-binding protein MIP-T3, putative
— OG7
TcCLB.508779.90 ⚠
structural maintenance of chromosome protein
— OG7
TcCLB.507813.10 ⚠
structural maintenance of chromosome 3 protei
— OG7
TcCLB.507035.110 ⚠
cAMP response protein 1, putative
— OG7
TcCLB.507739.20 ⚠
mitochondrial ATP-dependent zinc metallopepti
— OG7
TcCLB.504009.40 ⚠
Axonemal inner arm dynein light chain, putati
— OG7
TcCLB.510311.70 ⚠
26S protease regulatory subunit, putative, se
— OG7
TcCLB.506859.20 ⚠
proteasome regulatory ATPase subunit 5, putat
— OG7
TcCLB.503885.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510879.50 ⚠
regulatory subunit of protein kinase a-like p
— OG7
TcCLB.508989.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504147.200 ⚠
19S proteasome regulatory subunit, Regulatory
— OG7
TcCLB.511047.50 ⚠
proteasome regulatory ATPase subunit 2, putat
— OG7
TcCLB.508647.210 ⚠
dynein arm light chain, putative
— OG7
TcCLB.507875.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508489.40 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.