TcCLB.507813.10

structural maintenance of chromosome 3 protein, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_101525 OG7: OG7_0001761 200 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 200 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.504137.60 ⚠
beta adaptin, putative
— OG7
TcCLB.508239.30 ⚠
neurobeachin/beige-like protein, putative
— OG7
TcCLB.506857.90 ⚠
proteasome regulatory ATPase subunit 1, putat
— OG7
TcCLB.510243.50 ⚠
UMP/CMP kinase, putative
— OG7
TcCLB.504029.101 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511047.50 ⚠
proteasome regulatory ATPase subunit 2, putat
— OG7
TcCLB.504147.200 ⚠
19S proteasome regulatory subunit, Regulatory
— OG7
TcCLB.511217.100 ⚠
cullin 3, putative
— OG7
TcCLB.511803.10 ⚠
cullin 2, putative
— OG7
TcCLB.507389.10 ⚠
Flagellum attachment zone protein 14
— OG7
TcCLB.510879.50 ⚠
regulatory subunit of protein kinase a-like p
— OG7
TcCLB.503885.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510535.60 ⚠
ccr4-not transcription complex subunit
— OG7
TcCLB.511113.9 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcCLB.506859.20 ⚠
proteasome regulatory ATPase subunit 5, putat
— OG7
TcCLB.510311.70 ⚠
26S protease regulatory subunit, putative, se
— OG7
TcCLB.504009.40 ⚠
Axonemal inner arm dynein light chain, putati
— OG7
TcCLB.506941.9 ⚠
endosomal trafficking protein RME-8, putative
— OG7
TcCLB.509073.30 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.507739.20 ⚠
mitochondrial ATP-dependent zinc metallopepti
— OG7
TcCLB.509499.38 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507035.110 ⚠
cAMP response protein 1, putative
— OG7
TcCLB.507395.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511143.12 ⚠
Microtubule-binding protein MIP-T3, putative
— OG7
TcCLB.508779.90 ⚠
structural maintenance of chromosome protein
— OG7
TcCLB.509011.20 ⚠
RNA polymerase IIA largest subunit, putative
— OG7
TcCLB.510105.50 ⚠
fibrillarin, putative
— OG7
TcCLB.511435.49 ⚠
phosphatidylinositol 3-kinase, putative
— +2 more OG7
TcCLB.506223.120 ⚠
phosphatidylinositol 3-related kinase, putati
— +2 more OG7
TcCLB.410961.10 ⚠
phosphatidylinositol kinase related protein,
— +2 more OG7
TcCLB.507603.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507817.80 ⚠
5'-3' exoribonuclease A, putative (fragment)
— OG7
TcCLB.511305.10 ⚠
5'-3' exoribonuclease B, putative
— OG7
TcCLB.506351.9 ⚠
5'-3' exoribonuclease A, putative (fragment)
— OG7
TcCLB.507641.80 ⚠
5'-3' exoribonuclease D, putative
— OG7
TcCLB.506221.30 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.420989.10 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.507603.200 ⚠
proteasome regulatory ATPase subunit 3, putat
— OG7
TcCLB.509951.49 ⚠
DNA-directed RNA polymerase II subunit 2, put
— OG7
TcCLB.503777.19 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcCLB.509103.10 ⚠
pre-mRNA splicing factor 19, putative
— OG7
TcCLB.510755.19 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510105.40 ⚠
cullin-like protein, putative
— OG7
TcCLB.509151.80 ⚠
SpoU rRNA Methylase family, putative
— OG7
TcCLB.504159.80 ⚠
histone deacetylase, putative
— OG7
TcCLB.507641.14 ⚠
neurobeachin/beige protein, putative
— OG7
TcCLB.509247.30 ⚠
CCR4-NOT transcription complex subunit 1
— OG7
TcCLB.506925.150 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.506659.39 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.507213.10 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.