TcCLB.509499.38

hypothetical protein, conserved
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_144327 OG7: OG7_0042734 44 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 44 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.510535.60
ccr4-not transcription complex subunit
— Both
TcCLB.510055.70
Kinetochore interacting protein 5, putative
— OG7
TcCLB.510073.70
CCR4-NOT transcription complex subunit 2, put
— Both
TcCLB.506529.460 ⚠
TPR repeat, putative
— Both
TcCLB.506755.160
AAA ATPase, putative
— Both
TcCLB.504043.10
General negative regulator of transcription s
— Both
TcCLB.503903.70 ⚠
hypothetical protein, conserved
— Both
TcCLB.508387.160 ⚠
Phosphatidylinositol 4-phosphate 5-kinase, pu
— OG7
TcCLB.509965.350 ⚠
ubiquitin-protein ligase, putative
— OG7
TcCLB.511217.160 ⚠
WW domain containing protein, putative
— OG7
TcCLB.507875.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510491.10 ⚠
Anaphase-promoting complex, cyclosome, subuni
— OG7
TcCLB.506503.90
Flagellum attachment zone protein 7
— OG6
TcCLB.506533.34 ⚠
phosphatidylinositol kinase related protein,
— OG7
TcCLB.506223.120 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
TcCLB.410961.10 ⚠
phosphatidylinositol kinase related protein,
— OG7
TcCLB.507389.10 ⚠
Flagellum attachment zone protein 14
— OG7
TcCLB.504029.101
hypothetical protein, conserved
— OG7
TcCLB.507099.40
Concanavalin A-like lectin/glucanases superfa
— OG7
TcCLB.504835.29 ⚠
Flagellum attachment zone protein 14
— OG7
TcCLB.507813.10 ⚠
structural maintenance of chromosome 3 protei
— OG7
TcCLB.507011.60 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
TcCLB.503531.49 ⚠
structural maintenance of chromosome 3, putat
— OG7
TcCLB.509805.10
cAMP-dependent protein kinase catalytic subun
— OG6
TcCLB.508779.90 ⚠
structural maintenance of chromosome protein
— Both
TcCLB.508387.90
paraflagellar rod protein, putative
— Both
TcCLB.506769.120 ⚠
Mucin-associated surface protein (MASP), subg
— OG6
TcCLB.511605.30 ⚠
mucin TcMUCII, putative
— OG6
TcCLB.509103.10
pre-mRNA splicing factor 19, putative
— Both
TcCLB.506941.9
endosomal trafficking protein RME-8, putative
— Both
TcCLB.504427.260
kinesin-C
— OG6
TcCLB.506215.19
intraflagellar transport protein 140, putativ
— Both
TcCLB.505807.40
hypothetical protein, conserved
— Both
TcCLB.507509.89 ⚠
cleavage and polyadenylation specificity fact
— Both
TcCLB.509247.30
CCR4-NOT transcription complex subunit 1
— Both
TcCLB.507511.10 ⚠
cleavage and polyadenylation specificity fact
— Both
TcCLB.504033.180
hypothetical protein, conserved
— Both
TcCLB.506401.350
Dynein heavy chain, N-terminal region 2, puta
— OG6
TcCLB.508787.10
hypothetical protein, conserved
— Both
TcCLB.510351.80
Pre-mRNA polyadenylation factor FIP1
— Both
TcCLB.511435.49 ⚠
phosphatidylinositol 3-kinase, putative
— Both
TcCLB.507873.20
cell differentiation protein, putative
— Both
TcCLB.508725.10 ⚠
CCR4-NOT transcription complex subunit 10, pu
— Both
TcCLB.508727.9 ⚠
CCR4-NOT transcription complex subunit 10, pu
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.