TcCLB.505807.40

hypothetical protein, conserved
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_134892 OG7: OG7_0037731 114 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 114 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.507739.20 ⚠
mitochondrial ATP-dependent zinc metallopepti
— OG7
TcCLB.510325.60
hypothetical protein, conserved
— Both
TcCLB.508647.120
hypothetical protein, conserved
— Both
TcCLB.506925.30 ⚠
Regulatory-associated protein of TOR1
— Both
TcCLB.506857.90 ⚠
proteasome regulatory ATPase subunit 1, putat
— Both
TcCLB.507603.20 ⚠
translation initiation factor EIF-2b alpha su
— Both
TcCLB.506755.160
AAA ATPase, putative
— Both
TcCLB.503903.70 ⚠
hypothetical protein, conserved
— Both
TcCLB.508837.170 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506865.40 ⚠
guanine nucleotide exchange factor subunit GC
— OG7
TcCLB.509835.20 ⚠
translation initiation factor eIF2B delta sub
— OG7
TcCLB.510161.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510159.19 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcCLB.507735.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508387.160 ⚠
Phosphatidylinositol 4-phosphate 5-kinase, pu
— OG7
TcCLB.509965.350 ⚠
ubiquitin-protein ligase, putative
— OG7
TcCLB.511217.160 ⚠
WW domain containing protein, putative
— OG7
TcCLB.507875.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507809.119
Autophagy protein Apg6, putative
— OG7
TcCLB.506635.40 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TcCLB.510105.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508439.30 ⚠
regulator of chromosome condensation 1-like p
— OG7
TcCLB.506773.180 ⚠
regulator of chromatin condensation, putative
— OG7
TcCLB.510593.10 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TcCLB.510055.70
Kinetochore interacting protein 5, putative
— OG7
TcCLB.503557.20 ⚠
ankyrin repeat protein, putative
— OG7
TcCLB.510611.40 ⚠
Ankyrin repeats (3 copies), putative
— OG7
TcCLB.507603.200 ⚠
proteasome regulatory ATPase subunit 3, putat
— OG7
TcCLB.507213.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507813.10 ⚠
structural maintenance of chromosome 3 protei
— OG7
TcCLB.510101.340
hypothetical protein, conserved
— OG7
TcCLB.506227.150 ⚠
protein kinase A regulatory subunit
— OG7
TcCLB.510879.50 ⚠
regulatory subunit of protein kinase a-like p
— OG7
TcCLB.507035.110 ⚠
cAMP response protein 1, putative
— OG7
TcCLB.508489.40
hypothetical protein, conserved
— OG7
TcCLB.504835.29 ⚠
Flagellum attachment zone protein 14
— OG7
TcCLB.510105.120
protein kinase, putative
— OG7
TcCLB.507099.40
Concanavalin A-like lectin/glucanases superfa
— OG7
TcCLB.507389.10 ⚠
Flagellum attachment zone protein 14
— OG7
TcCLB.511143.12 ⚠
Microtubule-binding protein MIP-T3, putative
— OG7
TcCLB.504029.101
hypothetical protein, conserved
— OG7
TcCLB.503531.49 ⚠
structural maintenance of chromosome 3, putat
— OG7
TcCLB.507011.60 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
TcCLB.504147.200 ⚠
19S proteasome regulatory subunit, Regulatory
— OG7
TcCLB.506223.80 ⚠
Metalloprotease M41 FtsH, putative
— OG7
TcCLB.510105.210 ⚠
mitochondrial ATP-dependent zinc metallopepti
— OG7
TcCLB.511047.50 ⚠
proteasome regulatory ATPase subunit 2, putat
— OG7
TcCLB.504009.40 ⚠
Axonemal inner arm dynein light chain, putati
— OG7
TcCLB.506859.20 ⚠
proteasome regulatory ATPase subunit 5, putat
— OG7
TcCLB.510311.70 ⚠
26S protease regulatory subunit, putative, se
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.