TcCLB.509835.20

translation initiation factor eIF2B delta subunit, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_101847 OG7: OG7_0001817 64 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 64 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.508489.40 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510105.50 ⚠
fibrillarin, putative
— OG7
TcCLB.510105.210 ⚠
mitochondrial ATP-dependent zinc metallopepti
— OG7
TcCLB.508145.49 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508347.159 ⚠
microtubule-associated protein, putative, (fr
— OG7
TcCLB.506659.10 ⚠
tc40 antigen-like, putative, immunodominant a
— OG7
TcCLB.506223.80 ⚠
Metalloprotease M41 FtsH, putative
— OG7
TcCLB.508837.170 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504043.10 ⚠
General negative regulator of transcription s
— OG7
TcCLB.507603.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509967.170 ⚠
dynein arm light chain, putative
— OG7
TcCLB.506215.19 ⚠
intraflagellar transport protein 140, putativ
— OG7
TcCLB.505807.40 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510515.80 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511365.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511621.150 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507011.60 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
TcCLB.503531.49 ⚠
structural maintenance of chromosome 3, putat
— OG7
TcCLB.508647.210 ⚠
dynein arm light chain, putative
— OG7
TcCLB.508989.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509965.350 ⚠
ubiquitin-protein ligase, putative
— OG7
TcCLB.511217.160 ⚠
WW domain containing protein, putative
— OG7
TcCLB.507875.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506755.160 ⚠
AAA ATPase, putative
— OG7
TcCLB.506773.40 ⚠
3-methylcrotonoyl-CoA carboxylase beta subuni
— OG7
TcCLB.508387.90 ⚠
paraflagellar rod protein, putative
— OG7
TcCLB.507817.80 ⚠
5'-3' exoribonuclease A, putative (fragment)
— OG7
TcCLB.511305.10 ⚠
5'-3' exoribonuclease B, putative
— OG7
TcCLB.506351.9 ⚠
5'-3' exoribonuclease A, putative (fragment)
— OG7
TcCLB.507641.80 ⚠
5'-3' exoribonuclease D, putative
— OG7
TcCLB.510101.340 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504033.180 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510311.70 ⚠
26S protease regulatory subunit, putative, se
— OG7
TcCLB.509205.10 ⚠
translation initiation factor EIF-2B subunit,
— Both
TcCLB.509203.79 ⚠
translation initiation factor EIF-2B subunit,
— Both
TcCLB.507603.20 ⚠
translation initiation factor EIF-2b alpha su
— Both
TcCLB.507603.200 ⚠
proteasome regulatory ATPase subunit 3, putat
— OG7
TcCLB.509247.30 ⚠
CCR4-NOT transcription complex subunit 1
— OG7
TcCLB.507213.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511143.12 ⚠
Microtubule-binding protein MIP-T3, putative
— OG7
TcCLB.508779.90 ⚠
structural maintenance of chromosome protein
— OG7
TcCLB.507813.10 ⚠
structural maintenance of chromosome 3 protei
— OG7
TcCLB.507035.110 ⚠
cAMP response protein 1, putative
— OG7
TcCLB.450155.9 ⚠
Nucleoporin NUP76
— OG7
TcCLB.506533.34 ⚠
phosphatidylinositol kinase related protein,
— OG7
TcCLB.507739.20 ⚠
mitochondrial ATP-dependent zinc metallopepti
— OG7
TcCLB.504009.40 ⚠
Axonemal inner arm dynein light chain, putati
— OG7
TcCLB.511435.49 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
TcCLB.506865.40 ⚠
guanine nucleotide exchange factor subunit GC
— Both
TcCLB.506859.20 ⚠
proteasome regulatory ATPase subunit 5, putat
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.