TcCLB.508779.90

structural maintenance of chromosome protein 4, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_101113 OG7: OG7_0001761 207 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 207 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.506775.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507803.49 ⚠
histone deacetylase, putative
— OG7
TcCLB.506357.130 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507923.40 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503989.60 ⚠
protein phosphatase 2C, putative (fragment)
— OG7
TcCLB.504427.140 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508369.50 ⚠
acetyl-CoA carboxylase (fragment)
— OG7
TcCLB.403789.9 ⚠
DNA-directed RNA polymerase I largest subunit
— OG7
TcCLB.506925.150 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.508239.30 ⚠
neurobeachin/beige-like protein, putative
— OG7
TcCLB.503595.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.505943.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510243.50 ⚠
UMP/CMP kinase, putative
— OG7
TcCLB.508921.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506941.260 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510879.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504029.101 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510747.130 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511047.50 ⚠
proteasome regulatory ATPase subunit 2, putat
— OG7
TcCLB.505123.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506503.110 ⚠
DNA-directed RNA polymerases I and III subuni
— OG7
TcCLB.504147.200 ⚠
19S proteasome regulatory subunit, Regulatory
— OG7
TcCLB.507809.100 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511217.100 ⚠
cullin 3, putative
— OG7
TcCLB.511803.10 ⚠
cullin 2, putative
— OG7
TcCLB.507389.10 ⚠
Flagellum attachment zone protein 14
— OG7
TcCLB.506661.110 ⚠
WD domain, G-beta repeat/Dip2/Utp12 Family, p
— OG7
TcCLB.505807.270 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.510755.19 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510599.14 ⚠
acetyl-CoA carboxylase (fragment)
— OG7
TcCLB.503653.50 ⚠
histone deacetylase, putative
— OG7
TcCLB.503777.19 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcCLB.504137.60 ⚠
beta adaptin, putative
— OG7
TcCLB.507813.10 ⚠
structural maintenance of chromosome 3 protei
— OG7
TcCLB.511143.12 ⚠
Microtubule-binding protein MIP-T3, putative
— OG7
TcCLB.510841.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507395.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507035.110 ⚠
cAMP response protein 1, putative
— OG7
TcCLB.508131.19 ⚠
Glycosyl hydrolase family 65 central catalyti
— OG7
TcCLB.510311.70 ⚠
26S protease regulatory subunit, putative, se
— OG7
TcCLB.510879.50 ⚠
regulatory subunit of protein kinase a-like p
— OG7
TcCLB.503813.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503893.150 ⚠
Right handed beta helix region/Periplasmic co
— OG7
TcCLB.503885.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511113.9 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcCLB.506859.20 ⚠
proteasome regulatory ATPase subunit 5, putat
— OG7
TcCLB.504009.40 ⚠
Axonemal inner arm dynein light chain, putati
— OG7
TcCLB.507739.20 ⚠
mitochondrial ATP-dependent zinc metallopepti
— OG7
TcCLB.509073.30 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.506739.200 ⚠
pyruvate dehydrogenase phosphatase
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.