TcCLB.506503.110

DNA-directed RNA polymerases I and III subunit RPAC1, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_102180 OG7: OG7_0003550 102 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 102 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.510879.30
hypothetical protein, conserved
— Both
TcCLB.507923.40
hypothetical protein, conserved
— Both
TcCLB.509011.20 ⚠
RNA polymerase IIA largest subunit, putative
— +2 more Both
TcCLB.509951.49 ⚠
DNA-directed RNA polymerase II subunit 2, put
— Both
TcCLB.504119.4 ⚠
DNA-directed RNA polymerase III subunit C1, p
— +2 more Both
TcCLB.511417.40 ⚠
DNA-directed RNA polymerase III, putative
— Both
TcCLB.511801.44 ⚠
DNA-dependent RNA polymerases, putative
— Both
TcCLB.506925.40 ⚠
RNA polymerase I second largest subunit, puta
— OG7
TcCLB.403789.9 ⚠
DNA-directed RNA polymerase I largest subunit
— +1 more Both
TcCLB.443683.9 ⚠
DNA-directed rna polymerase I largest subunit
— +1 more Both
TcCLB.506949.10 ⚠
DNA-directed rna polymerase I largest subunit
— +1 more Both
TcCLB.507467.94 ⚠
hypothetical protein, conserved
— OG7
TcCLB.401473.9 ⚠
DNA-directed RNA polymerase I largest subunit
— +1 more Both
TcCLB.508839.89 ⚠
DNA-directed rna polymerase I largest subunit
— +1 more Both
TcCLB.506863.50 ⚠
ribosomal RNA processing protein 45, putative
— OG7
TcCLB.503777.19 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcCLB.506755.20
paraflagellar rod component, putative
— OG7
TcCLB.510167.29
ribosomal RNA processing protein 4, putative,
— OG7
TcCLB.506925.110
hypothetical protein, conserved
— OG7
TcCLB.503885.40
hypothetical protein, conserved
— OG7
TcCLB.503821.10 ⚠
RNA-binding protein RBP10, putative, DNA-dire
— OG7
TcCLB.509453.40 ⚠
DNA-directed RNA polymerase I subunit RPB10,
— OG7
TcCLB.507485.15 ⚠
DNA-directed RNA polymerase subunit, putative
— OG7
TcCLB.507485.34 ⚠
DNA-directed RNA polymerase III subunit, puta
— OG7
TcCLB.507673.65 ⚠
DNA-directed RNA polymerase subunit, putative
— OG7
TcCLB.504159.80 ⚠
histone deacetylase, putative
— OG7
TcCLB.504051.20 ⚠
ATP-dependent DNA DEAD/DEAH box helicase, put
— OG7
TcCLB.509769.70 ⚠
DNA polymerase theta (helicase domain only),
— OG7
TcCLB.510755.19 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509965.350 ⚠
ubiquitin-protein ligase, putative
— OG7
TcCLB.510243.50 ⚠
UMP/CMP kinase, putative
— OG7
TcCLB.511217.160 ⚠
WW domain containing protein, putative
— OG7
TcCLB.510753.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507875.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511395.70
hypothetical protein, conserved
— OG7
TcCLB.507509.30 ⚠
RNA polymerase-like protein, putative
— OG7
TcCLB.506265.120
hypothetical protein, conserved
— OG7
TcCLB.511423.104
DNA-directed RNA polymerase 2, RPB12 subunit,
— OG7
TcCLB.506135.110
mitochondrial RNA binding complex 1 subunit,
— OG7
TcCLB.511583.30
hypothetical protein, conserved
— OG7
TcCLB.510525.90 ⚠
histone H2A, putative
— OG7
TcCLB.510525.110 ⚠
histone H2A, putative
— OG7
TcCLB.508321.21 ⚠
histone H2A, putative
— OG7
TcCLB.510525.100 ⚠
histone H2A, putative
— OG7
TcCLB.510525.80 ⚠
histone H2A, putative
— OG7
TcCLB.508321.11 ⚠
histone H2A, putative (fragment)
— OG7
TcCLB.510143.90
hypothetical protein, conserved
— OG7
TcCLB.509073.30 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.506503.150 ⚠
histone H3 variant V
— OG7
TcCLB.510749.40 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.