TcCLB.443683.9

DNA-directed rna polymerase I largest subunit, putative (fragment)
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_101773 OG7: OG7_0001854 181 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 181 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.511417.40 ⚠
DNA-directed RNA polymerase III, putative
— +1 more OG7
TcCLB.509951.49 ⚠
DNA-directed RNA polymerase II subunit 2, put
— +1 more OG7
TcCLB.503777.19 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcCLB.506607.19 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcCLB.510431.250 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcCLB.508717.30 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcCLB.507809.30 ⚠
ribose-phosphate pyrophosphokinase, putative
— Both
TcCLB.506925.40 ⚠
RNA polymerase I second largest subunit, puta
— +3 more Both
TcCLB.506503.110 ⚠
DNA-directed RNA polymerases I and III subuni
— +1 more Both
TcCLB.510599.14 ⚠
acetyl-CoA carboxylase (fragment)
— Both
TcCLB.508369.50 ⚠
acetyl-CoA carboxylase (fragment)
— Both
TcCLB.511217.100 ⚠
cullin 3, putative
— OG7
TcCLB.506779.60 ⚠
DNA-direcetd RNA polymerase II, subunit 9, pu
— OG7
TcCLB.510029.40 ⚠
DNA-directed RNA polymerase III subunit C11,
— OG7
TcCLB.508321.11 ⚠
histone H2A, putative (fragment)
— OG7
TcCLB.510525.80 ⚠
histone H2A, putative
— OG7
TcCLB.510525.100 ⚠
histone H2A, putative
— OG7
TcCLB.508321.21 ⚠
histone H2A, putative
— OG7
TcCLB.510525.110 ⚠
histone H2A, putative
— OG7
TcCLB.510525.90 ⚠
histone H2A, putative
— OG7
TcCLB.509103.20 ⚠
tubulin-tyrosine ligase, putative
— OG7
TcCLB.506775.30 ⚠
tubulin-tyrosine ligase-like protein, putativ
— OG7
TcCLB.503897.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508995.30 ⚠
tubulin-tyrosine ligase, putative
— OG7
TcCLB.506941.80 ⚠
tubulin-tyrosine ligase-like protein, putativ
— OG7
TcCLB.510141.20 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
TcCLB.506885.270 ⚠
tubulin tyrosine ligase, putative
— OG7
TcCLB.507485.15 ⚠
DNA-directed RNA polymerase subunit, putative
— OG7
TcCLB.507485.34 ⚠
DNA-directed RNA polymerase III subunit, puta
— OG7
TcCLB.507673.65 ⚠
DNA-directed RNA polymerase subunit, putative
— OG7
TcCLB.509011.20 ⚠
RNA polymerase IIA largest subunit, putative
— OG7
TcCLB.506949.10 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
TcCLB.403789.9 ⚠
DNA-directed RNA polymerase I largest subunit
— OG7
TcCLB.506221.30 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.420989.10 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.507641.14 ⚠
neurobeachin/beige protein, putative
— OG7
TcCLB.506659.39 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.509379.10 ⚠
dihydrolipoamide dehydrogenase, putative
— OG7
TcCLB.509151.80 ⚠
SpoU rRNA Methylase family, putative
— OG7
TcCLB.510105.40 ⚠
cullin-like protein, putative
— OG7
TcCLB.504137.60 ⚠
beta adaptin, putative
— OG7
TcCLB.511127.140 ⚠
DNA replication licensing factor MCM4, putati
— OG7
TcCLB.507395.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511313.30 ⚠
formin, putative
— OG7
TcCLB.506533.34 ⚠
phosphatidylinositol kinase related protein,
— OG7
TcCLB.511435.49 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
TcCLB.511113.9 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcCLB.503425.29 ⚠
DNA replication licensing factor MCM8, putati
— OG7
TcCLB.510293.40 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
TcCLB.503955.70 ⚠
eukaryotic translation initiation factor 2 be
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.