TcCLB.506773.40

3-methylcrotonoyl-CoA carboxylase beta subunit, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_101933 OG7: OG7_0003085 41 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 41 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.504835.20
3-methylcrotonyl-CoA carboxylase, putative
— Both
TcCLB.508165.170
Mucin-associated surface protein (MASP), subg
— OG7
TcCLB.504247.79 ⚠
transmembrane protein, conserved (fragment)
— Both
TcCLB.509351.10
delta-1-pyrroline-5-carboxylate dehydrogenase
— Both
TcCLB.506519.130 ⚠
GMP reductase
— OG6
TcCLB.507211.40 ⚠
inosine-5'-monophosphate dehydrogenase, putat
— Both
TcCLB.511351.9 ⚠
inosine-5'-monophosphate dehydrogenase, putat
— Both
TcCLB.511469.100
2-oxoisovalerate dehydrogenase beta subunit,
— Both
TcCLB.508781.110
2-oxoisovalerate dehydrogenase alpha subunit,
— Both
TcCLB.507809.119
Autophagy protein Apg6, putative
— OG7
TcCLB.508205.4 ⚠
hypothetical protein, conserved
— OG7
TcCLB.449247.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511429.10 ⚠
transmembrane protein, conserved (fragment)
— Both
TcCLB.506865.40 ⚠
guanine nucleotide exchange factor subunit GC
— OG7
TcCLB.506925.220
hypothetical protein, conserved
— OG7
TcCLB.507669.14 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506529.220
hypothetical protein, conserved
— OG7
TcCLB.511801.10 ⚠
leucine rich repeat
— OG7
TcCLB.510105.120
protein kinase, putative
— OG7
TcCLB.509835.20 ⚠
translation initiation factor eIF2B delta sub
— OG7
TcCLB.511555.110
Domain of unknown function (DUF4486), putativ
— OG7
TcCLB.508717.30 ⚠
phosphoribosylpyrophosphate synthetase, putat
— Both
TcCLB.507757.70 ⚠
dihydrolipoamide dehydrogenase, putative, ace
— Both
TcCLB.506607.19 ⚠
phosphoribosylpyrophosphate synthetase, putat
— Both
TcCLB.506375.110
(H+)-ATPase G subunit, putative
— Both
TcCLB.507809.30 ⚠
ribose-phosphate pyrophosphokinase, putative
— Both
TcCLB.503777.19 ⚠
phosphoribosylpyrophosphate synthetase, putat
— Both
TcCLB.508373.10
glutamine dependent carbamoyl-phosphate synth
— Both
TcCLB.509379.10 ⚠
dihydrolipoamide dehydrogenase, putative
— Both
TcCLB.511589.10
ATP synthase, putative
— Both
TcCLB.510431.250 ⚠
phosphoribosylpyrophosphate synthetase, putat
— Both
TcCLB.511753.30
kinesin, putative
— Both
TcCLB.507603.20 ⚠
translation initiation factor EIF-2b alpha su
— Both
TcCLB.503579.20
hypothetical protein, conserved
— OG6
TcCLB.508723.70
AAA domain containing protein, putative
— Both
TcCLB.506941.194
hypothetical protein, conserved
— Both
TcCLB.510101.350
hypothetical protein, conserved
— Both
TcCLB.503811.70
bardet-biedl syndrome 7 protein
— Both
TcCLB.507507.30
Bardet-Biedl syndrome 9 protein
— Both
TcCLB.511363.4
hypothetical protein, conserved
— Both
TcCLB.507757.60 ⚠
dihydrolipoamide dehydrogenase, putative
— Both
Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.