TcCLB.509351.10

delta-1-pyrroline-5-carboxylate dehydrogenase, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_102275 OG7: OG7_0000710 39 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 39 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.508717.30 ⚠
phosphoribosylpyrophosphate synthetase, putat
— +2 more Both
TcCLB.506375.110
(H+)-ATPase G subunit, putative
— Both
TcCLB.505983.9 ⚠
tryparedoxin peroxidase, putative
— Both
TcCLB.508781.20
ATP synthase, putative
— Both
TcCLB.510431.250 ⚠
phosphoribosylpyrophosphate synthetase, putat
— +2 more Both
TcCLB.509499.14 ⚠
peroxidoxin
— Both
TcCLB.507809.30 ⚠
ribose-phosphate pyrophosphokinase, putative
— +1 more Both
TcCLB.510599.14 ⚠
acetyl-CoA carboxylase (fragment)
— Both
TcCLB.503777.19 ⚠
phosphoribosylpyrophosphate synthetase, putat
— +1 more Both
TcCLB.510101.140
pyruvate phosphate dikinase, putative
— Both
TcCLB.506025.50
Vacuolar proton pump subunit B, putative
— Both
TcCLB.506773.40
3-methylcrotonoyl-CoA carboxylase beta subuni
— Both
TcCLB.511589.200
S-adenosylhomocysteine hydrolase, putative
— Both
TcCLB.511589.10
ATP synthase, putative
— Both
TcCLB.511001.190
vacuolar ATP synthase subunit d, putative
— Both
TcCLB.487507.10 ⚠
tryparedoxin peroxidase, putative
— Both
TcCLB.511469.100
2-oxoisovalerate dehydrogenase beta subunit,
— Both
TcCLB.506529.516
ATP synthase subunit, putative
— Both
TcCLB.506857.110
Uncharacterised protein family UPF0066, putat
— Both
TcCLB.508951.20
hexokinase, putative
— Both
TcCLB.507389.70
peptidase, putative, metallo-peptidase, Clan
— Both
TcCLB.504119.29 ⚠
deoxyhypusine synthase, putative
— Both
TcCLB.510997.30
hypothetical protein, conserved
— Both
TcCLB.504017.79 ⚠
glycyl-tRNA synthetase, putative
— Both
TcCLB.511421.60 ⚠
deoxyhypusine synthase, putative
— Both
TcCLB.506351.80 ⚠
serine peptidase, clan SC, family S9A-like pr
— Both
TcCLB.508539.30
hypothetical protein, conserved
— Both
TcCLB.511557.10 ⚠
oligopeptidase b
— Both
TcCLB.510737.100
Peroxin 19
— Both
TcCLB.509167.100
valyl-tRNA synthetase, putative
— Both
TcCLB.511589.260 ⚠
glycyl-tRNA synthetase, putative
— Both
TcCLB.511049.40
leucyl-tRNA synthetase, putative
— Both
TcCLB.506945.50
T-complex protein 11, putative
— Both
TcCLB.510557.50 ⚠
mucin TcMUCII, putative
— OG6
TcCLB.506405.120
V-type ATPase, A subunit, putative
— Both
TcCLB.508369.50 ⚠
acetyl-CoA carboxylase (fragment)
— Both
TcCLB.509445.10 ⚠
tryparedoxin peroxidase, putative
— Both
TcCLB.510565.30
cytochrome c oxidase subunit V, putative
— Both
TcCLB.506607.19 ⚠
phosphoribosylpyrophosphate synthetase, putat
— +1 more Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.