TcCLB.487507.10

tryparedoxin peroxidase, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_100111 OG7: OG7_0001516 42 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 42 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.506375.110 ⚠
(H+)-ATPase G subunit, putative
— Both
TcCLB.418069.10 ⚠
heat shock protein 70 (hsp70), putative (frag
— OG6
TcCLB.506135.9 ⚠
heat shock 70 kDa protein, putative (fragment
— OG6
TcCLB.506743.4 ⚠
eukaryotic translation initiation factor 1A,
— Both
TcCLB.511211.160 ⚠
heat shock protein 70 (hsp70), putative
— OG6
TcCLB.511211.220 ⚠
heat shock protein 70, putative
— OG6
TcCLB.511211.170 ⚠
heat shock protein 70 (hsp70), putative
— OG6
TcCLB.509543.50 ⚠
DNAK protein, putative
— OG6
TcCLB.508813.15 ⚠
heat shock protein 70, putative (fragment)
— OG6
TcCLB.511067.30 ⚠
transketolase, putative
— Both
TcCLB.510565.30 ⚠
cytochrome c oxidase subunit V, putative
— Both
TcCLB.508951.20 ⚠
hexokinase, putative
— Both
TcCLB.505843.10 ⚠
glutamate dehydrogenase, putative
— Both
TcCLB.508277.160 ⚠
glutaminyl-tRNA synthetase, putative
— Both
TcCLB.509445.39 ⚠
glutamate dehydrogenase, putative
— Both
TcCLB.511069.4 ⚠
transketolase, putative
— Both
TcCLB.511139.40 ⚠
ATP-dependent RNA helicase SUB2, putative (fr
— OG7
TcCLB.511585.190 ⚠
Eukaryotic initiation factor 4A-1
— OG7
TcCLB.482471.19 ⚠
ATP-dependent RNA helicase SUB2, putative (fr
— OG7
TcCLB.511731.60 ⚠
glutamyl-tRNA synthetase, putative
— OG7
TcCLB.506885.413 ⚠
glyceraldehyde-3-phosphate dehydrogenase, put
— OG7
TcCLB.511531.50 ⚠
glucosamine-6-phosphate isomerase, putative,
— Both
TcCLB.461165.16 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— Both
TcCLB.506943.50 ⚠
glyceraldehyde 3-phosphate dehydrogenase, put
— Both
TcCLB.508537.10 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— Both
TcCLB.510105.230 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— Both
TcCLB.506943.60 ⚠
glyceraldehyde 3-phosphate dehydrogenase, put
— Both
TcCLB.506409.240 ⚠
glyceraldehyde 3-phosphate dehydrogenase, C-t
— Both
TcCLB.510911.50 ⚠
glycine cleavage system P-protein, putative,
— Both
TcCLB.422507.10 ⚠
glycine dehydrogenase [decarboxylating], puta
— Both
TcCLB.506367.10 ⚠
isovaleryl-coA dehydrogenase, putative (fragm
— Both
TcCLB.509829.20 ⚠
isovaleryl-coA dehydrogenase, putative
— Both
TcCLB.503405.10 ⚠
glutamine synthetase
— Both
TcCLB.511589.200 ⚠
S-adenosylhomocysteine hydrolase, putative
— Both
TcCLB.510101.140 ⚠
pyruvate phosphate dikinase, putative
— Both
TcCLB.511199.9 ⚠
ATP-dependent RNA helicase FAL1, putative (fr
— Both
TcCLB.503639.10 ⚠
inositol-3-phosphate synthase, putative
— Both
TcCLB.510181.9 ⚠
inositol-3-phosphate synthase, putative (frag
— Both
TcCLB.509351.10 ⚠
delta-1-pyrroline-5-carboxylate dehydrogenase
— Both
TcCLB.509445.10 ⚠
tryparedoxin peroxidase, putative
— +2 more Both
TcCLB.505983.9 ⚠
tryparedoxin peroxidase, putative
— +2 more Both
TcCLB.509499.14 ⚠
peroxidoxin
— +2 more Both
Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.