TcCLB.506367.10

isovaleryl-coA dehydrogenase, putative (fragment)
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_102105 OG7: OG7_0001034 43 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 43 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.507993.390 ⚠
pyruvate kinase 2, putative
— Both
TcCLB.511069.4 ⚠
transketolase, putative
— Both
TcCLB.511531.50 ⚠
glucosamine-6-phosphate isomerase, putative,
— Both
TcCLB.487507.10 ⚠
tryparedoxin peroxidase, putative
— Both
TcCLB.503575.50 ⚠
fatty acyl CoA synthetase, putative
— Both
TcCLB.507641.60 ⚠
aldehyde dehydrogenase, putative
— Both
TcCLB.505843.30 ⚠
DNA repair protein Rad9, putative
— Both
TcCLB.506625.60 ⚠
inositol 5-phosphatase 1, putative
— Both
TcCLB.436535.19 ⚠
Glucose-6-phosphate dehydrogenase, putative
— Both
TcCLB.506953.49 ⚠
glucose-6-phosphate 1-dehydrogenase, glucose-
— Both
TcCLB.506529.508 ⚠
glucose-6-phosphate isomerase, glycosomal, pu
— Both
TcCLB.503589.10 ⚠
GDP-mannose pyrophosphorylase
— Both
TcCLB.506265.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.486901.10 ⚠
endonuclease/exonuclease/phosphatase, putativ
— OG7
TcCLB.506147.30 ⚠
synaptojanin (N-terminal domain), putative, i
— OG7
TcCLB.461165.16 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG7
TcCLB.506943.50 ⚠
glyceraldehyde 3-phosphate dehydrogenase, put
— OG7
TcCLB.508537.10 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG7
TcCLB.510105.230 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG7
TcCLB.511731.60 ⚠
glutamyl-tRNA synthetase, putative
— OG7
TcCLB.506943.60 ⚠
glyceraldehyde 3-phosphate dehydrogenase, put
— OG7
TcCLB.506409.240 ⚠
glyceraldehyde 3-phosphate dehydrogenase, C-t
— OG7
TcCLB.509499.14 ⚠
peroxidoxin
— Both
TcCLB.506605.170 ⚠
inosine-guanine nucleoside hydrolase, putativ
— Both
TcCLB.511067.30 ⚠
transketolase, putative
— Both
TcCLB.508731.60 ⚠
adenylosuccinate synthetase, putative
— Both
TcCLB.506945.160 ⚠
S-adenosylmethionine synthetase, putative
— Both
TcCLB.503405.10 ⚠
glutamine synthetase
— Both
TcCLB.509445.10 ⚠
tryparedoxin peroxidase, putative
— Both
TcCLB.506885.413 ⚠
glyceraldehyde-3-phosphate dehydrogenase, put
— Both
TcCLB.511579.9 ⚠
fatty acyl CoA syntetase 1, putative (fragmen
— Both
TcCLB.505983.9 ⚠
tryparedoxin peroxidase, putative
— Both
TcCLB.504153.360 ⚠
succinyl-coA:3-ketoacid-coenzyme A transferas
— Both
TcCLB.508585.10 ⚠
hypothetical protein, conserved
— Both
TcCLB.511581.10 ⚠
fatty acyl CoA synthetase 2, putative
— Both
TcCLB.504431.100 ⚠
guanine deaminase, putative
— Both
TcCLB.506829.110 ⚠
fatty acyl CoA synthetase 2, putative
— Both
TcCLB.510911.50 ⚠
glycine cleavage system P-protein, putative,
— Both
TcCLB.511581.20 ⚠
fatty acyl CoA syntetase 1 (fragment)
— Both
TcCLB.506829.100 ⚠
fatty acyl CoA syntetase 1, putative
— Both
TcCLB.422507.10 ⚠
glycine dehydrogenase [decarboxylating], puta
— Both
TcCLB.508277.160 ⚠
glutaminyl-tRNA synthetase, putative
— Both
TcCLB.510101.140 ⚠
pyruvate phosphate dikinase, putative
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.